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Recombinant Human EPHA1

Cat.No. : EPHA1-28577TH
Product Overview : Recombinant fragment of Human Eph receptor A1 expressed in a Baculovirus infected Sf9 cell expression system with N-terminal proprietary tag, MWt 72kDa..
  • Specification
  • Gene Information
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Description : This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
Protein length : 408 amino acids
Molecular Weight : 72.000kDa inclusive of tags
Source : Baculovirus
Biological activity : The Specific activity of EPHA1-28577TH was determined to be 28 nmol/min/mg.
Form : Liquid
Purity : Densitometry
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name : EPHA1 EPH receptor A1 [ Homo sapiens ]
Official Symbol : EPHA1
Synonyms : EPHA1; EPH receptor A1; EphA1 , EPHT, EPHT1; ephrin type-A receptor 1; EPH;
Gene ID : 2041
mRNA Refseq : NM_005232
Protein Refseq : NP_005223
MIM : 179610
Uniprot ID : P21709
Chromosome Location : 7q32-q36
Pathway : Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; EPHA forward signaling, organism-specific biosystem;
Function : ATP binding; nucleotide binding; protein kinase activity; protein kinase binding; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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