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Recombinant Human MET

Cat.No. : MET-29608TH
Product Overview : Recombinant fragment, corresponding to amino acids 956-1390 of Human Met with N-terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system, 81kDa.
  • Specification
  • Gene Information
  • Related Products
Description : The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
Biological activity : The Specific activity of MET-29608TH was determined to be 44 nmol/min/mg.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the protein kinase superfamily. Tyr protein kinase family.Contains 3 IPT/TIG domains.Contains 1 protein kinase domain.Contains 1 Sema domain.
Gene Name : MET met proto-oncogene (hepatocyte growth factor receptor) [ Homo sapiens ]
Official Symbol : MET
Synonyms : MET; met proto-oncogene (hepatocyte growth factor receptor); hepatocyte growth factor receptor; HGFR; RCCP2;
Gene ID : 4233
mRNA Refseq : NM_000245
Protein Refseq : NP_000236
MIM : 164860
Uniprot ID : P08581
Chromosome Location : 7q31
Pathway : Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Arf6 signaling events, organism-specific biosystem; Axon guidance, organism-specific biosystem;
Function : ATP binding; hepatocyte growth factor-activated receptor activity; nucleotide binding; protein binding; protein tyrosine kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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