Recombinant Human NLK

• Cat.No.: NLK-28098TH
• Product Overview: Recombinant full length Human NLK with an N terminal proprietary tag; 84 kDa inclusive of tag.

Specification

• Description: Role in cell fate determination, required for differentiation of bone marrow stromal cells.
• Protein length: 527 amino acids
• Molecular Weight: 84.000kDa inclusive of tags
• Source: Baculovirus infected sf9 cells
• Biological activity: Specific activity: 2.4 nmol/min/mg
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.Contains 1 protein kinase domain.

Gene Information

• Gene Name: NLK nemo-like kinase [ Homo sapiens ]
• Official Symbol: NLK
• Synonyms: NLK; nemo-like kinase; nemo like kinase; serine/threonine-protein kinase NLK
• Gene ID: 51701
• mRNA Refseq: NM_016231
• Protein Refseq: NP_057315
• MIM: 609476
• Uniprot ID: Q9UBE8
• Chromosome Location: 17q11.2
• Pathway: Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem
• Function: ATP binding; MAP kinase activity; SH2 domain binding; magnesium ion binding; nucleotide binding