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Native Mushroom Agaricus bisporus Lectin (ABA/ABL), Ferritin-Conjugated

Cat.No. : ABA/ABL-252M
Product Overview : Native Mushroom Agaricus bisporus Lectin (ABA/ABL) - Ferritin
Blood Group Specificity: Non-specific
Preferred Sugar Specificity: Galactoseβ1-3N-Acetylgalactosamine
Inhibiting or Eluting Sugar: Fetuin
Divalent Ions: None Required
Mitogenic Activity: No
Hazardous Shipping: Non-hazardous
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Description : Agaricus bisporus agglutinin (ABA) is an affinity-purified tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-β-1,3-N-acetylgalactosamine and another for galactose-β-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins. Agaricus bisporus Lectin (ABA/ABL) is conjugated to ferritin, that has a molecular weight of 474,000 g/mol (all 24 subunits combined). Ferritin-conjugated ABA/ABL can be used to visualize localization of specific saccharide moieties and examine the distribution of plasma membrane glycoproteins. These conjugates can be viewed via electron microscopy.
Source : Mushroom
Species : Mushroom
Form : Liquid
Purity : High Purity Grade
Stability : Shelf Life: 1 year
Storage : At 2-8 centigrade.
Concentration : 1 mg/mL
Official Symbol : ABA/ABL
Synonyms : Agaricus bisporus Lectin; ABA/ABL
Official Symbol : ABA/ABL
Synonyms : Agaricus bisporus Lectin; ABA/ABL

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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