| Description : |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
67.1 kDa |
| AA Sequence : |
MADKLTRIAIVNHDKCKPKKCRQEC KKSCPVVRMGKLCIEVTPQSKIAWI SETLCIGCGICIKKCPFGALSIVNL PSNLEKETTHRYCANAFKLHRLPIP RPGEVLGLVGTNGIGKSTALKILAG KQKPNLGKYDDPPDWQEILTYFRGS ELQNYFTKILEDDLKAIIKPQYVDQ IPKAAKGTVGSILDRKDETKTQAIV CQQLDLTHLKERNVEDLSGGELQRF ACAVVCIQKADIFMFDEPSSYLDVK QRLKAAITIRSLINPDRYIIVVEHD LSVLDYLSDFICCLYGVPSAYGVVT MPFSVREGINIFLDGYVPTENLRFR DASLVFKVAETANEEEVKKMCMYKY PGMKKKMGEFELAIVAGEFTDSEIM VMLGENGTGKTTFIRMLAGRLKPDE GGEVPVLNVSYKPQKISPKSTGSVR QLLHEKIRDAYTHPQFVTDVMKPLQ IENIIDQEVQTLSGGELQRVALALC LGKPADVYLIDEPSAYLDSEQRLMA ARVVKRFILHAKKTAFVVEHDFIMA TYLADRVIVFDGVPSKNTVANSPQT LLAGMNKFLSQLEITFRRDPNNYRP RINKLNSIKDVEQKKSGNYFFLDDT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
