Recombinant Human CACYBP, GST-tagged

• Cat.No.: CACYBP-10648H
• Product Overview: Recombinant Human CACYBP protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-228a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CACYBP calcyclin binding protein [ Homo sapiens ]
• Official Symbol: CACYBP
• Synonyms: CACYBP; calcyclin binding protein; calcyclin-binding protein; S100A6BP; SIP; hCacyBP; S100A6-binding protein; Siah-interacting protein (SIP); growth-inhibiting gene 5 protein; GIG5; PNAS-107; RP1-102G20.6; MGC87971
• Gene ID: 27101
• mRNA Refseq: NM_001007214
• Protein Refseq: NP_001007215
• MIM: 606186
• UniProt ID: Q9HB71
• Chromosome Location: 1q24-q25
• Pathway: Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem
• Function: protein binding; protein homodimerization activity