Active Recombinant Human KDR protein, hFc-tagged
Cat.No. : | KDR-643H |
Product Overview : | Recombinant Human KDR protein(NP_002244.1)(Met1-Glu764), fused with hFc tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | hFc |
Form : | Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Bio-activity : | 1. Immobilized Human VEGF121 at 2 μg/mL (100 μL/well) can bind Human VEGFR2/KDR (ECD, hFc Tag), the EC50 of Human VEGFR2/KDR (ECD, hFc Tag) is 6-48 ng/mL.2. Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 20-120 ng/mL in the presence of 10 ng/mL recombinant human VEGF165. |
Molecular Mass : | The recombinant human VEGFR2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 979 amino acids and predicts a molecular mass of 109 kDa. The apparent molecular mass of human VEGFR2/Fc monomer is approximatly 150-160 KDa in SDS-PAGE under reducing conditions due to glycosylation. |
Proteinlength : | Met1-Glu764 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC. |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | KDR kinase insert domain receptor (a type III receptor tyrosine kinase) [ Homo sapiens ] |
Official Symbol : | KDR |
Synonyms : | KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor; |
Gene ID : | 3791 |
mRNA Refseq : | NM_002253 |
Protein Refseq : | NP_002244 |
MIM : | 191306 |
UniProt ID : | P35968 |
Products Types
◆ Lysates | ||
KDR-1520MCL | Recombinant Mouse KDR cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1609 | KDR Activity Assay Kit | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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