Recombinant Human USP28 protein, His/Myc-tagged

• Cat.No.: USP28-153H
• Product Overview: Recombinant Human USP28(1-583 aa) fused with His tag at N-terminal and Myc tag at C-terminalwas expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers.
• Source: E. coli
• Species: Human
• Tag: His/Myc
• Form: Tris-based buffer,50% glycerol
• Protein length: 1-583 aa
• AA Sequence: MTAELQQDDAAGAADGHGSSCQMLL NQLREITGIQDPSFLHEALKASNGD ITQAVSLLTD ERVKEPSQDTVATEPSEVEGSAANK EVLAKVIDLTHDNKDDLQAAIALSL LESPKIQADG RDLNRMHEATSAETKRSKRKRCEVW GENPNPNDWRRVDGWPVGLKNVGNT CWFSAVIQSL FQLPEFRRLVLSYSLPQNVLENCRS HTEKRNIMFMQELQYLFALMMGSNR KFVDPSAALD LLKGAFRSSEEQQQDVSEFTHKLLD WLEDAFQLAVNVNSPRNKSENPMVQ LFYGTFLTEG VREGKPFCNNETFGQYPLQVNGYRN LDECLEGAMVEGDVELLPSDHSVKY GQERWFTKLP PVLTFELSRFEFNQSLGQPEKIHNK LEFPQIIYMDRYMYRSKELIRNKRE CIRKLKEEIK ILQQKLERYVKYGSGPARFPLPDML KYVIEFASTKPASESCPPESDTHMT LPLSSVHCSV SDQTSKESTSTESSSQDVESTFSSP EDSLPKSKPLTSSRSSMEMPSQPAP RTVTDEEINF VKTCLQRWRSEIEQDIQDLKTCIAS TTQTIEQMYCDPLLRQVE
• Purity: >90% ( SDS-PAGE )
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
  Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.

Gene Information

• Gene Name: USP28 ubiquitin specific peptidase 28 [ Homo sapiens ]
• Official Symbol: USP28
• Synonyms: USP28; ubiquitin specific peptidase 28; ubiquitin specific protease 28; ubiquitin carboxyl-terminal hydrolase 28; KIAA1515; ubiquitin thioesterase 28; deubiquitinating enzyme 28; ubiquitin thiolesterase 28; ubiquitin-specific-processing protease 28
• Gene ID: 57646
• mRNA Refseq: NM_020886
• Protein Refseq: NP_065937
• MIM: 610748
• UniProt ID: Q96RU2
• Chromosome Location: 11q23
• Function: cysteine-type peptidase activity; peptidase activity; protein binding; ubiquitin thiolesterase activity; ubiquitin thiolesterase activity; ubiquitin-specific protease activity