Active Recombinant SARS-CoV S1 Subunit Protein, His-tagged
| Cat.No. : | S-05S |
| Product Overview : | Recombinant SARS-CoV spike S1 subunit (14-667 aa) fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
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| Description : | attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 and CLEC4M/DC-SIGNR receptors and internalization of the virus into the endosomes of the host cell induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes. |
| Source : | HEK293 |
| Species : | SARS-CoV |
| Tag : | His |
| Form : | Liquid |
| Bio-activity : | Measured by its binding ability in a functional ELISA with Human ACE-2. |
| Molecular Mass : | 73.7kDa |
| Protein length : | 660 |
| AA Sequence : | SDLDRCTTFDDVQAPNYTQHTSSMR GVYYPDEIFRSDTLYLTQDLFLPFY SNVTGFHTINHTFGNPVIPFKDGIY FAATEKSNVVRGWVFGSTMNNKSQS VIIINNSTNVVIRACNFELCDNPFF AVSKPMGTQTHTMIFDNAFNCTFEY ISDAFSLDVSEKSGNFKHLREFVFK NKDGFLYVYKGYQPIDVVRDLPSGF NTLKPIFKLPLGINITNFRAILTAF SPAQDIWGTSAAAYFVGYLKPTTFM LKYDENGTITDAVDCSQNPLAELKC SVKSFEIDKGIYQTSNFRVVPSGDV VRFPNITNLCPFGEVFNATKFPSVY AWERKKISNCVADYSVLYNSTFFST FKCYGVSATKLNDLCFSNVYADSFV VKGDDVRQIAPGQTGVIADYNYKLP DDFMGCVLAWNTRNIDATSTGNYNY KYRYLRHGKLRPFERDISNVPFSPD GKPCTPPALNCYWPLNDYGFYTTTG IGYQPYRVVVLSFELLNAPATVCGP KLSTDLIKNQCVNFNFNGLTGTGVL TPSSKRFQPFQQFGRDVSDFTDSVR DPKTSEILDISPCAFGGVSVITPGT NASSEVAVLYQDVNCTDVSTAIHAD QLTPAWRIYSTGNNVFQTQAGCLIG AEHVDTSYECDIPIGAGICASYHTV SLLR |
| Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
| Purity : | > 90% by SDS-PAGE |
| Applications : | SDS-PAGE, Bioactivity |
| Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
| Concentration : | 0.25 mg/mL (determined by Absorbance at 280nm) |
| Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
| Gene Name : | S spike glycoprotein [ SARS coronavirus Tor2 ] |
| Official Symbol : | S |
| Synonyms : | S; spike glycoprotein; E2 |
| Gene ID : | 1489668 |
| Protein Refseq : | NP_828851 |
| UniProt ID : | P59594 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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