A4GNT Protein, alpha-1,4-N-acetylglucosaminyltransferase

A4GNT

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A4GNT

Official Full Name alpha-1,4-N-acetylglucosaminyltransferase
Background This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane.
Synonyms A4GNT; alpha-1,4-N-acetylglucosaminyltransferase; alpha4GnT; MGC149493
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Tag :
    • His
    • DHFR
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human A4GNT-16H Recombinant Human A4GNT, His-tagged HEK293 His
    Human A4GNT-17H Recombinant Human A4GNT, His-DHFR-tagged E.coli His/DHFR
    Human A4GNT-9162HCL Recombinant Human A4GNT 293 Cell Lysate HEK293 N/A

    A4GNT involved in several pathways and played different roles in them. We selected most pathways A4GNT participated on our site, such as Metabolism of proteins, O-linked glycosylation, O-linked glycosylation of mucins, which may be useful for your reference. Also, other proteins which involved in the same pathway with A4GNT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of proteins MGAT4B; GALNT6; TMED2; RHBDL1; EEF1A1; MGAT4A; SMC5; MUC1; SPON2; SENP5
    O-linked glycosylation C8orf84; MUC13; MUC5AC; B3GALTL; ST6GALNAC2; MUC15; ADAMTS5; MUC21; GCNT3; GALNTL5
    O-linked glycosylation of mucins MUC12; MUCL1; A4GNT; ST6GALNAC2; MUC21; GALNT5; MUC5AC; MUC4; B3GNT2A; MUC20
    Post-translational protein modification TRAPPC10; ADAMTSL5; UBA2; ADAMTS18; PPP6R1; MUCL1; MUC13; ADAMTS15; NEU3; SUMF2
    heparan sulfate biosynthesis A4GNT; HS3ST4; MAPK1IP1L
    heparan sulfate biosynthesis (late stages) HS3ST4; A4GNT

    A4GNT has several biochemical functions, for example, acetylglucosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by A4GNT itself. We selected most functions A4GNT had, and list some proteins which have the same functions with A4GNT. You can find most of the proteins on our site.

    Function Related Protein
    acetylglucosaminyltransferase activity MGAT1A; DPY19L1; B3GNT9-PS; POC1BL; GALNT18A; MGAT1; OGT; C3orf39; GALNTL4; POMGNT2

    A4GNT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with A4GNT here. Most of them are supplied by our site. Hope this information will be useful for your research of A4GNT.

    Karasawa, F; Shiota, A; et al. Essential role of gastric gland mucin in preventing gastric cancer in mice. JOURNAL OF CLINICAL INVESTIGATION 122:923-934(2012).
    Nakayama, J; Katsuyama, T; et al. Recent progress in paradoxical concanavalin A staining. ACTA HISTOCHEMICA ET CYTOCHEMICA 33:153-157(2000).

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