ABCA3
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Official Full Name
ATP-binding cassette, sub-family A (ABC1), member 3
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Overview
ATP-binding cassette sub-family A member 3 is a protein that in humans is encoded by the ABCA3 gene. -
Synonyms
ABCA3; ATP-binding cassette, sub-family A (ABC1), member 3; ABC3; ATP-binding cassette sub-family A member 3; ABC C; EST111653; LBM180; ABC transporter 3; ABC-C transporter; ATP-binding cassette transporter 3; ABC-C; SMDP3; MGC72201; MGC166979;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- His|T7
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ABCA3-546H | Recombinant Human ABCA3 | Mammalian Cell | His | ||
Human | ABCA3-9205H | Recombinant Human ABCA3, GST-tagged | E.coli | GST | 1-209a.a. | |
Human | ABCA3-8114H | Recombinant Human ABCA3 protein, His & T7-tagged | E.coli | His/T7 | Asp1358~Phe1635 (Accession # Q99758) | |
Human | ABCA3-2HCL | Recombinant Human ABCA3 lysate | HEK293 | N/A | ||
Human | ABCA3-1861H | Recombinant Human ABCA3 protein, GST-tagged | E.coli | GST | 1606 - 1704 aa | |
Human | ABCA3-2399H | Recombinant Human ABCA3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | ABCA3-2399H-B | Recombinant Human ABCA3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | ABCA3-0508H | Recombinant Human ABCA3 Protein (Asp1358-Phe1635), N-His-tagged | E.coli | N-His | Asp1358-Phe1635 | |
Mouse | ABCA3-1079M | Recombinant Mouse ABCA3 Protein | Mammalian Cell | His | ||
Mouse | ABCA3-181M-B | Recombinant Mouse ABCA3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | ABCA3-181M | Recombinant Mouse ABCA3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
- Involved Pathway
- Protein Function
- Interacting Protein
- ABCA3 Related Articles
ABCA3 involved in several pathways and played different roles in them. We selected most pathways ABCA3 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ABC transporters | Abca2;TAP2;ABCC4;ABCG2;ABCA7;ABCB9;ABCB7;ABCC3;ABCD2 |
ABCA3 has several biochemical functions, for example, ATP binding, ATPase activity, coupled to transmembrane movement of substances, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCA3 itself. We selected most functions ABCA3 had, and list some proteins which have the same functions with ABCA3. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | P2RX2;PRKACA;PARS2;HSP90AA1.1;BAZ1B;ZAP70;MATK;KCNJ11;DNAJA1 |
ATPase activity, coupled to transmembrane movement of substances | ABCA1B;ABCB6;ABCA1;Abcb1b;ABCA6;ABCB4;ABCG2D;ABCC3;ABCA7 |
transporter activity | LCN9;SLCO1A4;AP4B1;CHP1;SLC4A2A;TTPAL;AP1S2;CPNE6;SEC22A |
ABCA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCA3.
CANX; LAMP3
- Q&As
- Reviews
Q&As (10)
Ask a questionABCA3 catalyzes the ATP-dependent transport of phospholipids such as phosphatidylglycerol and phosphatidylcholine from the cytoplasm to the lumen of the lamellar bodies, and then participates in lamellar bodies biogenesis and homeostasis of lung surfactant. Preferential transport of phosphatidylcholine containing short acyl chains. In addition, it acts as an efflux transporter for miltefosine across the macrophage membrane, as well as through intralumenal vesicles to remove free cholesterol (FC) as a surfactant component and protect cells from free cholesterol toxicity.
The purity of our recombinant proteins is generally above 80%. And we can produce higher purity ABCA3 protein according to your requirements, such as crystalline grade protein.
Of course, in addition to this, we will provide MSDS files.
We can detect and remove endotoxins from protein products upon request. Please consult our technical experts for specific services.
ABCA3 transporters may be involved in the development of resistance to xenobiotics and engulfment during programmed cell death.
ABCA3 is a member of the superfamily of ATP-binding cassette (ABC) transporters and a member of the ABC1 subfamily.
Our experts can perform customized protein expression according to the research needs of our customers.
His and GST tags are commonly used for purification and are beneficial for improving protein solubility and downstream applications.
Our recombinant ABCA3 proteins are expressed from E. coli and mammalian cells.
ABCA3 is a highly conserved transmembrane protein that plays a key role in regulating pulmonary surfactant homeostasis, and mutations in this protein have been increasingly recognized as a cause of inherited lung disease.
Customer Reviews (3)
Write a reviewCreative BioMart's technical experts are very professional, quick and friendly.
I used recombinant ABCA3 protein as a positive control for WB, and the experiment worked well.
Creative BioMart's recombinant proteins are highly pure and immunoreactivity, making them ideal for assays based on antigen-antibody reactions.
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