abcf1
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  • Official Full Name
  • ATP-binding cassette, sub-family F (GCN20), member 1
  • Background
  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.
  • Synonyms
  • ABCF1; ATP-binding cassette, sub-family F (GCN20), member 1; ABC50; ATP-binding cassette sub-family F member 1; EST123147; TNF-alpha-stimulated ABC protein; TNFalpha-inducible ATP-binding protein; ATP-binding cassette 50 (TNF-alpha stimulated); ABC27
Cat.#:ABCF1-26041THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ABCF1, His-tagged
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Cat.#:ABCF1-059HTag:GST
Source (Host):Wheat Germ (in vitro)Species:Human
Product nameRecombinant Human ABCF1 Protein, GST-Tagged
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Cat.#:Abcf1-8138MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Abcf1 protein, His & T7-tagged
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Cat.#:ABCF1-412RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ABCF1 Protein
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Cat.#:ABCF1-183RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ABCF1 Protein, His-tagged
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Cat.#:ABCF1-12398ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ABCF1
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Cat.#:ABCF1-7HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ABCF1 cell lysate
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Involved Pathway

ABCF1 involved in several pathways and played different roles in them. We selected most pathways ABCF1 participated on our site, such as ABC-family proteins mediated transport, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCF1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ABC-family proteins mediated transport
APOA1B; ABCA8; ABCA7; EIF2S1A; ABCE1; KCNJ11; ABCG4B; ABCB8; ABCA4A; ABCC9
Transmembrane transport of small molecules
SLC6A6A; ATP7B; SLC29A3; AQP8A.1; SLC41A1; TFR1B; SLC22A15; ATP1A1A.4; SLC17A7A; CLCN4-2

Protein Function

ABCF1 has several biochemical functions, for example, ATP binding, ATPase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCF1 itself. We selected most functions ABCF1 had, and list some proteins which have the same functions with ABCF1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein MAP2K2A; RPS6KA4; IQCA1; NLRP14; FARS2; NSF; ABCD1; PIK3R4; SMCHD1; PRKDC
Function ATPase activity
Related Protein ABCG2A; MYH8; PEX6; MACF1; KIF2B; MYH7; SWSAP1; DQX1; BLM; PSMC2
Function poly(A) RNA binding
Related Protein XPO5; PSMC1; RPS3A; RPL18A; HSPB1; FAM32A; PA2G4; ARF1; CDK5R2; SLC16A3
Function protein binding
Related Protein RECQL; INTS7; CARM1; VASNA; C9orf86; C8orf74; DDX18; PHYH; NEK6; PLXDC1
Function ribosome binding
Related Protein MTRF1; MTOR; ICT1; RPSA; CPEB1B; RICTOR; CPEB3; IGHMBP2; CPEB1; EIF2S1
Function translation activator activity
Related Protein RPS27L; PAIP1; ABCF1; LARP1; DAZL; BOLL; PABPC1
Function translation factor activity, RNA binding
Related Protein GTF2H3; MTIF3; CPEB1A; EIF4A1; EIF2S2; EIF4G1; EIF4H; EIF2S3; EIF4G3; EEF1D

Interacting Protein

ABCF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCF1.
SRPK1; PINX1; LYAR; PRKAB1; ITGB3BP; CNOT1; ere_dna; NOP56; EED; FN1; Fbl; HDGF; SNW1; EMC2; IFI16; TIGD6; CDC5L