actr1a
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  • Official Full Name
  • ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
  • Background
  • This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size;from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of;cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle;formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per;dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is;approximately 60% identical at the amino acid level to conventional actin.
  • Synonyms
  • ACTR1A; ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); ARP1 (actin related protein 1, yeast) homolog A (centractin alpha); alpha-centractin; ARP1; actin related protein 1; Actin RPV; ACTR 1A; Alpha Centractin; ARP 1; ARP1 actin related protein 1 homolog A; ARP1 actin related protein 1 homolog A centractin alpha; ARP1 yeast homolog A; Centractin alpha; Centractin; Centrosome associated actin homolog; CTRN 1; CTRN1; FLJ52695; FLJ52800; FLJ55002; actin-RPV; centrosome-associated actin homolog
Cat.#:ACTR1A-26591THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ACTR1A, His-tagged
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Cat.#:ACTR1A-232HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ACTR1A Protein, GST-tagged
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Cat.#:ACTR1A-1252MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ACTR1A Protein
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Cat.#:Actr1a-3343RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Actr1a, His-tagged
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Cat.#:ACTR1A-488RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ACTR1A Protein
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Cat.#:ACTR1A-271CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ACTR1A Protein, His-tagged
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Cat.#:ACTR1A-226RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ACTR1A Protein, His-tagged
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Cat.#:ACTR1A-1806CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ACTR1A
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Cat.#:ACTR1A-9053HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ACTR1A 293 Cell Lysate
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Involved Pathway

ACTR1A involved in several pathways and played different roles in them. We selected most pathways ACTR1A participated on our site, such as Adaptive Immune System, Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACTR1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
PAG1; FGF20A; CLTC; LILRB5; KLRB1B; GAN; PJA1; LILRB1; ASB8; NCR3LG1
Anchoring of the basal body to the plasma membrane
TTBK2; B9D1; SCLT1; NPHP1; CCDC123; CENPJ; DCTN1; CEP76; CEP89; TUBG1
Assembly of the primary cilium
BBS5; KIF3A; MKKS; UNC119.1; IFT172; FLR; IFT27; BBS4; IFT20; SETD6
Cell Cycle
SET; NIPBL; GADD45B; MLF1IP; CENPJ; SDCCAG8; CCNB3; CDC25B; HTATIP; CDC16
Cell Cycle, Mitotic
FGFR1OP; CSNK1D; CEP76; STAG2; BANF1; NUP50; NCAPH2; POLD3; ODF2B; CSNK1E
Centrosome maturation
CENPJ; TSGA14; DCTN2; PLK4; DCTN3; DCTN1A; CCP110; CEP63; MAPRE1B; ODF2B
G2/M Transition
NUMA1; CCP110; DCTN3; DYNC1I2; TSGA14; TUBGCP3; TUBG2; MYBL2; TUBGCP2; OFD1
Immune System
SLAMF6; FCN1; UBR2; CFHL4; PELI3; MB21D1; CD300LF; CASPBL; WASF3; ACTR1A

Protein Function

ACTR1A has several biochemical functions, for example, ATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACTR1A itself. We selected most functions ACTR1A had, and list some proteins which have the same functions with ACTR1A. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ATAD2B; PSKH2; CDC42BPB; PRKACBA; AURKC; ACOT12; PHKG2; DCAMKL2; DDX24; PIP4K2B

Interacting Protein

ACTR1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACTR1A here. Most of them are supplied by our site. Hope this information will be useful for your research of ACTR1A.
Dctn1; Dctn2; Dctn3; HLA-B; Capza1; Actr1a; Cep76; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; ZFC3H1; PTBP3; CAPZA2; Dynlrb1; Nfyc; Cct2; Cct4; Prkcz; SNW1