ADCY1 Protein, adenylate cyclase 1 (brain)

ADCY1

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ADCY1

Official Full Name adenylate cyclase 1 (brain)
Background This gene encodes a form of adenylate cyclase expressed in brain. A similar protein in mouse is involved in pattern formation of the brain.
Synonyms ADCY1; adenylate cyclase 1 (brain); adenylate cyclase type 1; adenyl cyclase; Adenylate cyclase 1; adenylate cyclase type I; ATP pyrophosphate lyase; Brain adenylate cyclase 1; OTTHUMP00000207996; adenylyl cyclase 1; ATP pyrophosphate-lyase 1; 3,5-cyclic AMP synthetase; Ca(2+)/calmodulin-activated adenylyl cyclase; AC1
    • Species :
    • Bovine
    • Human
    • Mouse
    • Source :
    • E.coli
    • E.Coli or Yeast
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADCY1-137H Recombinant Human ADCY1 Mammalian Cell His
    Human ADCY1-6841H Recombinant Human ADCY1 protein, His & T7-tagged E.coli His/T7
    Mouse ADCY1-1342M Recombinant Mouse ADCY1 Protein Mammalian Cell His
    Mouse Adcy1-3171M Recombinant Mouse Adcy1, His-tagged E.Coli or Yeast His
    Mouse Adcy1-6842M Recombinant Mouse Adcy1 protein, His & T7-tagged E.coli His/T7
    Bovine ADCY1-3170B Recombinant Bovine ADCY1, GST-tagged E.Coli or Yeast GST

    ADCY1 involved in several pathways and played different roles in them. We selected most pathways ADCY1 participated on our site, such as Activation of GABAB receptors, Activation of NMDA receptor upon glutamate binding and postsynaptic events, Adenylate cyclase activating pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADCY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of GABAB receptors KCNJ9; KCNJ10; GNGT2A; KCNJ6; GNGT2B; KCNJ2A; KCNJ3; ADCY9; ADCY8; GNB3B
    Activation of NMDA receptor upon glutamate binding and postsynaptic events ADCY3; CREB1; CREB1B; NEFLB; AKAP9; CAMKK1B; PDPK1A; SLC14A2; NETO2; DLG4
    Adenylate cyclase activating pathway ADCY3; ADCY6; ADCY7; ADCY8; ADCY9; ADCY1
    Adenylate cyclase inhibitory pathway ADCY8; ADCY1; ADCY9; ADCY6; ADCY3; ADCY7
    Adrenergic signaling in cardiomyocytes AGTR1; CACNG7A; FXYD2; PPP2R1B; PRKCA; ATP1B2B; SLC9A1; ADRB2B; CAMK2A; CALM2
    Aldosterone synthesis and secretion ATF6B; ITPR1; PRKACA; ATF1; CAMK2A; PDE2A; ATF4; DAGLB; ITPR2; CREB3L2
    Amoebiasis LAMA2; IL-8; AASS; CD1d1; RAB5C; C8A; ARG2; COL4A4; PRKCB; RAB7B
    Aquaporin-mediated transport AQP10B; GNB5B; MIPA; AQP10; AQP1A.1; AQP9B; GNB5A; ADCY3; AQP6; PRKAR1AA

    ADCY1 has several biochemical functions, for example, ATP binding, adenylate cyclase activity, calcium- and calmodulin-responsive adenylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADCY1 itself. We selected most functions ADCY1 had, and list some proteins which have the same functions with ADCY1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding TTLL10; CDC42BPA; DCLK3; RYK; MAT2AB; PSMC1; PAK6; UBE2E1; MMAB; DDX25
    adenylate cyclase activity ADCY9; ADCY1B; Adcy4; ADCY3; GNAS; ADCY6; ADCY1A; ADCY7; ADCY8; ADCY2B
    calcium- and calmodulin-responsive adenylate cyclase activity ADCY1; ADCY8; ADCY6; ADCY3
    calmodulin binding MYH7; SPHK1; CAMK2G; CAMKVB; ITPKC; DAPK1; CAMSAP1; EPB41; NETO2; ASPM
    metal ion binding ZNF496; ZFP1; ACVR1; RTEL1; MOB1A; MAP3K4; PRKCZ; GNS; IRGF4; ANTXRL

    ADCY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADCY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADCY1.

    Wang, XZ; Maynard, JA; et al. The Bordetella Adenylate Cyclase Repeat-in-Toxin (RTX) Domain Is Immunodominant and Elicits Neutralizing Antibodies. JOURNAL OF BIOLOGICAL CHEMISTRY 290:3576-3591(2015).
    Chae, JJ; Park, YH; et al. Connecting Two Pathways Through Ca2+ Signaling: NLRP3 Inflammasome Activation Induced by a Hypermorphic PLCG2 Mutation. ARTHRITIS & RHEUMATOLOGY 67:563-567(2015).

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