adk
Share
  • Official Full Name
  • adenosine kinase
  • Background
  • This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • ADK; adenosine kinase; adenosine 5 phosphotransferase; AK; 5033405D03Rik; AI255373; AI987814; MGC6593; 2310026J05Rik; ADK_HUMAN; OTTHUMP00000019864; OTTHUMP00000019865; adenosine 5-phosphotransferase
Cat.#:ADK-1290ETag:His
Source (Host):E. coliSpecies:E.coli
Product nameRecombinant Escherichia coli ADK Protein (1-214 aa), His-tagged
+Inquiry
Cat.#:ADK-2233MTag:His-SUMO
Source (Host):E. coliSpecies:Mycobacterium Tuberculosis
Product nameRecombinant Mycobacterium Tuberculosis ADK Protein (1-181 aa), His-SUMO-tagged
+Inquiry
Cat.#:ADK-1366HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADK Protein, MYC/DDK-tagged
+Inquiry
Cat.#:ADK-493HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADK Protein, His-tagged
+Inquiry
Cat.#:Adk-245HTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adk Protein, His-tagged, Bioactivity Validated
+Inquiry
Cat.#:Adk-494MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adk Protein, His/GST-tagged
+Inquiry
Cat.#:ADK-1108STag:His-SUMO/MYC
Source (Host):E. coliSpecies:S. flexneri
Product nameRecombinant S. flexneri ADK Protein, His-SUMO/MYC-tagged
+Inquiry
Cat.#:ADK-26098THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADK, His-tagged
+Inquiry
Cat.#:ADK-1343HTag:His/GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human ADK, His & GST tagged
+Inquiry
Cat.#:ADK-2481HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Adenosine Kinase, His-tagged
+Inquiry
Cat.#:ADK-359HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADK Protein, GST-tagged
+Inquiry
Cat.#:ADK-1364MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ADK Protein
+Inquiry
Cat.#:Adk-3158MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Adk, His-tagged
+Inquiry
Cat.#:ADK-529RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ADK Protein
+Inquiry
Cat.#:ADK-250RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ADK Protein, His-tagged
+Inquiry
Cat.#:ADK-1640CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ADK
+Inquiry
Cat.#:ADK-0127BTag:His
Source (Host):E. coli or YeastSpecies:Bacillus subtilis
Product nameRecombinant Bacillus subtilis ADK protein, His-tagged
+Inquiry
Cat.#:ADK-2817STag:His
Source (Host):E. coli or YeastSpecies:Staphylococcus
Product nameRecombinant Staphylococcus epidermidis ATCC 12228 ADK protein, His-tagged
+Inquiry
Cat.#:ADK-904STag:His
Source (Host):E. coli or YeastSpecies:Streptomyces coelicolor A3(2)
Product nameRecombinant Streptomyces coelicolor A3(2) ADK protein, His-tagged
+Inquiry
Cat.#:ADK-505HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human ADK cell lysate
+Inquiry
Cat.#:Kit-0878Tag:
Source (Host):Species:
Product nameADK Phosphorylation Assay Kit
+Inquiry
Cat.#:Kit-0880Tag:
Source (Host):Species:
Product nameADK Assay Kit
+Inquiry

Involved Pathway

ADK involved in several pathways and played different roles in them. We selected most pathways ADK participated on our site, such as Metabolic pathways, Metabolism, Metabolism of nucleotides, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolic pathways
SDHD; CYP3A25; ST6GALNAC3; HADHA; MTM1; MTMR2; ACSL3; IMPDH1B; Ckmm; URAH
Metabolism
ABHD4; ISCUB; PDPR; BRSK2; Sult2a2; RHAG; B3GNT2A; CPOX; CYP2AD2; GLTPD1
Metabolism of nucleotides
ADSS; GRX2; DPYD; NUDT15; PROZA; NUDT16; DPYDA.1; ADAL; DTYMK; TM9SF1
Purine metabolism
ENTPD8; PNPT1; PRPS1B; PNP; NME1-NME2; POLR2J; ENPP1; AMPD2; NT5C1A; POLR1E
Purine salvage
ADAL; PNP5B; TM9SF1; ADK; DGUOK; ADA; DCK
adenine and adenosine salvage II
ADK
adenine and adenosine salvage VI
ADK
superpathway of purine nucleotide salvage
ADK

Protein Function

ADK has several biochemical functions, for example, ATP binding, adenosine kinase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADK itself. We selected most functions ADK had, and list some proteins which have the same functions with ADK. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ORC1L; IRAK4; ROS1; ATP2A2; KIF27; DDX27; PRKD3; ATP7B; FICD; PASK
Function adenosine kinase activity
Related Protein ADKB; ADKA; ADK
Function metal ion binding
Related Protein ERI3; ZFP879; VAV2; GART; BMP1B; NME3; PLA2G4AA; ZNF691; ZNF582; BCKDHA
Function poly(A) RNA binding
Related Protein RPS7; BST2; PRDX1; ALDOA; AKAP17A; MTIF2; EIF1AX; EZR; TOP2A; IMMT

Interacting Protein

ADK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADK here. Most of them are supplied by our site. Hope this information will be useful for your research of ADK.
btuB; FICD; SRD5A3; 15-deoxy-delta(12,14; bosutinib; imatinib; dasatinib; sch51344

ADK Related Articles

Pukazhvanthen, P; Anbarasu, D; et al. Assessing humoral immune response of 4 recombinant antigens for serodiagnosis of tuberculosis. TUBERCULOSIS 94:622-633(2014).
Cui, XA; Singh, B; et al. Subcellular localization of adenosine kinase in mammalian cells: The long isoform of AdK is localized in the nucleus. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 388:46-50(2009).