ahcyl1
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  • Official Full Name
  • adenosylhomocysteinase-like 1
  • Background
  • The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene.
  • Synonyms
  • AHCYL1; adenosylhomocysteinase-like 1; S adenosylhomocysteine hydrolase like 1; putative adenosylhomocysteinase 2; inositol 1; 4; 5 trisphosphate receptor binding protein; IRBIT; XPVKONA; adoHcyase 2; DC-expressed AHCY-like molecule; S-adenosyl-L-homocyst
Cat.#:AHCYL1-508HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human AHCYL1 Protein, MYC/DDK-tagged
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Cat.#:AHCYL1-456HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human AHCYL1 Protein, GST-tagged
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Cat.#:AHCYL1-457HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human AHDC1 Protein, GST-tagged
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Cat.#:AHCYL1-8459HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AHCYL1, His-tagged
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Cat.#:AHCYL1-859HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human AHCYL1
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Cat.#:AHCYL1-276RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey AHCYL1 Protein, His-tagged
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Cat.#:AHCYL1-2602CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AHCYL1
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Cat.#:AHCYL1-11441ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish AHCYL1
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Cat.#:AHCYL1-39HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human AHCYL1 cell lysate
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Involved Pathway

AHCYL1 involved in several pathways and played different roles in them. We selected most pathways AHCYL1 participated on our site, such as Adaptive Immune System, Antigen activates B Cell Receptor (BCR) leading to generation of second messengers, C-type lectin receptors (CLRs), which may be useful for your reference. Also, other proteins which involved in the same pathway with AHCYL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
ASB8; CTSH; RNF144B; RNF6; NRG3; TRIM69; KLRF1; CD300E; LILRA1; SIGLEC10
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
IGKC; BLK; AKR1C1; SRMS; PIK3AP1; STIM1B; AHCYL1; IGLC2; IGHM; IGKV1-5
C-type lectin receptors (CLRs)
CLEC4A; CLEC4D; MALT1; CREBBP; AHCYL1; CASP8L1; ITPR2; IL1B2; CLEC6A; TAB1
CLEC7A (Dectin-1) induces NFAT activation
AHCYL1
CLEC7A (Dectin-1) signaling
IL1B2; UBE2V1; AHCYL1; CASP8L1; MALT1; TAB1
Cysteine and methionine metabolism
CTH; MPST; MAT2A; BCAT1; GOT2B; AHCYL1; APIP; AGXT2; TST; DNMT3AB
DAG and IP3 signaling
AHCYL1; PRKAR1AA; ADRBK1
DAP12 interactions
FGF20A; DUSP5; CD300LB; SPNA2; AHCYL1; CSF2RB; SPRED3; SIGLEC14; FGF10B; AGO2

Protein Function

AHCYL1 has several biochemical functions, for example, RNA binding, NOT adenosylhomocysteinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AHCYL1 itself. We selected most functions AHCYL1 had, and list some proteins which have the same functions with AHCYL1. You can find most of the proteins on our site.
Function
Related Protein
Function RNA binding
Related Protein HNRNPH1; CTU1; NOVA1; SPI1; RBM24A; ALYREF; PUS7L; EIF2C3; PPIE; IMPDH2
Function NOT adenosylhomocysteinase activity
Related Protein AHCYL1; AHCYL2
Function protein binding
Related Protein C4orf46; BLOC1S4; GOLGA1; MESDC1; CPNE1; FES; KRTAP19-5; NTRK1; TUT1; SLC16A3

Interacting Protein

AHCYL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AHCYL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AHCYL1.
MEOX2; PSMD9; PPL; SOX30; tat; CDKN2C

AHCYL1 Related Articles

Ando, H; Kawaai, K; et al. IRBIT: A regulator of ion channels and ion transporters. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1843:2195-2204(2014).
Panagopoulos, I; Brandal, P; et al. Novel CSF1-S100A10 fusion gene and CSF1 transcript identified by RNA sequencing in tenosynovial giant cell tumors. INTERNATIONAL JOURNAL OF ONCOLOGY 44:1425-1432(2014).