• Official Full Name
  • annexin A3
  • Background
  • This gene encodes a member of the annexin family.Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways.This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
  • Synonyms
  • ANXA3; annexin A3; 1 2 cyclic inositol phosphate phosphodiesterase; 2-cyclic phosphate 2-phosphohydrolase; 35 alpha calcimedin; 35-alpha calcimedin; Annexin III; Annexin-3; AnnexinA3; AnnexinIII; ANX 3; ANX A3; ANX3; ANXA 3; ANXA3_HUMAN; Calcimedin 35 alpha; Inositol 1 2 cyclic phosphate 2 phosphohydrolase; Inositol 1; Lipocortin III; LipocortinIII; OTTHUMP00000160701; OTTHUMP00000219237; OTTHUMP00000219238; PAP III; PAP-III; PAPIII; Placental anticoagulant protein III; calcimedin 35-alpha; Annexin III (lipocortin III); inositol 1,2-cyclic phosphate 2-phosphohydrolase
Source (Host):YeastSpecies:Human
Product nameRecombinant Human ANXA3 Protein (5-322 aa), His-tagged
Source (Host):HEK293Species:Human
Product nameRecombinant Human ANXA3 Protein, MYC/DDK
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA3, His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA3
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ANXA3 protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA3, GST-tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Anxa3 protein, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ANXA3 Protein
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Anxa3 protein, His-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Anxa3, His-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ANXA3 Protein
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Annexin A3, His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Annexin A3
Source (Host):Species:Human
Product nameRecombinant Human ANXA3 293 Cell Lysate

Involved Pathway

ANXA3 involved in several pathways and played different roles in them. We selected most pathways ANXA3 participated on our site, such as Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Prostaglandin Synthesis and Regulation
CC10; S100A10; ANXA6; ANXA2; ANXA3; ANXA4; S100A6; ANXA5

Protein Function

ANXA3 has several biochemical functions, for example, calcium ion binding, calcium-dependent phospholipid binding, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA3 itself. We selected most functions ANXA3 had, and list some proteins which have the same functions with ANXA3. You can find most of the proteins on our site.
Related Protein
Function calcium ion binding
Related Protein CABP4; NCL; THBS1; SYT3; PLSCR3; PCDHGA2; SYTL4; RHBDL3; F7; PCDH1G3
Function calcium-dependent phospholipid binding
Related Protein C2CD4A; RPH3AL; ANXA3B; SYT5A; ANXA8; SYTL1; ANXA2B; CPNE3; ANXA3; SYT10
Function calcium-dependent protein binding
Related Protein CPNE3; ANXA6; MBL1; CALM3; PDCD6; C9orf9; MYO5A; TNNT3; CCDC167; PDCD6IP
Function phospholipase A2 inhibitor activity
Related Protein ANXA3; CC10; ANXA2; ANXA1

Interacting Protein

ANXA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA3.
TP53; UNC119; UBR1; EMG1; IGSF21; pi3p; ATF2

ANXA3 Related Articles

Hamelin-Peyron, C; Vlaeminck-Guillem, V; et al. Prostate cancer biomarker annexin A3 detected in urines obtained following digital rectal examination presents antigenic variability. CLINICAL BIOCHEMISTRY 47:901-908(2014).
Suzuki, T; Ikari, K; et al. PADI4 and HLA-DRB1 Are Genetic Risks for Radiographic Progression in RA Patients, Independent of ACPA Status: Results from the IORRA Cohort Study. PLOS ONE 8:-(2013).