anxa4
Share
  • Official Full Name
  • annexin A4
  • Background
  • Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways.ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization.Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity.ANX4 is almost exclusively expressed in epithelial cells.
  • Synonyms
  • ANXA4; annexin A4; ANX4; P32.5; PP4-X; PAP-II; annexin-4; protein II; endonexin I; lipocortin IV; chromobindin-4; 35-beta calcimedin; proliferation-inducing gene 28; proliferation-inducing protein 28; placental anticoagulant protein II; carbohydrate-bindi
Cat.#:ANXA4-1334HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA4 protein, His-tagged
+Inquiry
Cat.#:ANXA4-18HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ANXA4 protein, His-tagged
+Inquiry
Cat.#:ANXA4-634HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ANXA4 protein, GST-tagged
+Inquiry
Cat.#:ANXA4-9697HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANXA4, GST-tagged
+Inquiry
Cat.#:Anxa4-1336MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Anxa4 protein, His-tagged
+Inquiry
Cat.#:ANXA4-1716MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ANXA4 Protein
+Inquiry
Cat.#:Anxa4-1340RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Anxa4 protein, His-tagged
+Inquiry
Cat.#:Anxa4-3496RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat Anxa4, His-tagged
+Inquiry
Cat.#:ANXA4-339RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ANXA4 Protein, His-tagged
+Inquiry
Cat.#:ANXA4-1332DTag:His
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog ANXA4 protein, His-tagged
+Inquiry
Cat.#:ANXA4-9640ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ANXA4
+Inquiry
Cat.#:ANXA4-1331CTag:His/T7
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle ANXA4 protein, His & T7-tagged
+Inquiry
Cat.#:ANXA4-1338PTag:His
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig ANXA4 protein, His-tagged
+Inquiry
Cat.#:ANXA4-1842Tag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Annexin A4
+Inquiry
Cat.#:ANXA4-8831HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ANXA4 293 Cell Lysate
+Inquiry

Involved Pathway

ANXA4 involved in several pathways and played different roles in them. We selected most pathways ANXA4 participated on our site, such as Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANXA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Prostaglandin Synthesis and Regulation
ANXA6; CC10; ANXA5; S100A10; S100A6; ANXA3; ANXA2; ANXA4

Protein Function

ANXA4 has several biochemical functions, for example, NF-kappaB binding, calcium ion binding, calcium-dependent phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANXA4 itself. We selected most functions ANXA4 had, and list some proteins which have the same functions with ANXA4. You can find most of the proteins on our site.
Function
Related Protein
Function NF-kappaB binding
Related Protein FOXP3; RNF25; FAF1; CPNE1; SNAI1A; HSPA6; ANXA4; EP300; NPM1; BRMS1
Function calcium ion binding
Related Protein PCDH2AB12; C2CD4B; SLC24A2; FSTL1; CALB1; SLC25A13; SYT5B; SLC25A23B; S100P; CRELD1
Function calcium-dependent phospholipid binding
Related Protein SYT5A; PLA2G4B; ANXA11A; SYT17; SYTL2; CPNE1; SYT2; TC2N; ANXA11; SYT1
Function calcium-dependent protein binding
Related Protein RAC3; CHP; TNNC1; ANXA6; CHP1; CALM2; SNAP25; S100P; S100B; NRXN1
Function identical protein binding
Related Protein MYD88; PFKL; PVRL2; FAS; EDC3; DYNLT1F; BNIP2; TRADD; FHOD1; EIF2AK3
Function phospholipase inhibitor activity
Related Protein ANGPTL3; ANXA4; SNCB; ANXA2B; ANXA1C; ANXA5; ANXA3B; ANXA3A; ANXA2A; APOC1
Function protein binding
Related Protein BEX5; ILKAP; SEC63; F11R; BLZF1; UBE2R2; LNPEP; EPB41; NDUFA13; CDC16

Interacting Protein

ANXA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANXA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANXA4.
TINF2; Cdk1; NMT2; SMPD1; POT1; pi3p; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; GABARAPL1