APOC4 Protein, apolipoprotein C-IV


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Official Full Name apolipoprotein C-IV
Background This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.
Synonyms APOC4; apolipoprotein C-IV; APO C4; Apo CIV; APOC 4; ApoC IV; Apolipoprotein C IV; apolipoprotein C4; APO-CIV; APOC-IV
    • Species :
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Wheat germ
    • Source :
    • E.coli
    • E.Coli or Yeast
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human APOC4-1334H Recombinant Human APOC4 Protein (27-127 aa), His-tagged Yeast His
    Human APOC4-9761H Recombinant Human APOC4, GST-tagged E.coli GST
    Human APOC4-98HCL Recombinant Human APOC4 cell lysate N/A
    Mouse APOC4-1790M Recombinant Mouse APOC4 Protein Mammalian Cell His
    Mouse Apoc4-1855M Recombinant Mouse Apoc4 protein, His & GST-tagged E.coli His/GST
    Rat Apoc4-3570R Recombinant Rat Apoc4, GST-tagged E.Coli or Yeast GST
    Rat APOC4-724R Recombinant Rat APOC4 Protein Mammalian Cell His
    Rabbit APOC4-3571R Recombinant Rabbit APOC4, GST-tagged E.Coli or Yeast GST
    Wheat germ APOC4-281H Recombinant Human APOC4, GST-tagged Wheat Germ N/A

    APOC4 involved in several pathways and played different roles in them. We selected most pathways APOC4 participated on our site, such as Statin Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with APOC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Statin Pathway APOC1; CETP; APOC4; PDIA2

    APOC4 has several biochemical functions, for example, lipid transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by APOC4 itself. We selected most functions APOC4 had, and list some proteins which have the same functions with APOC4. You can find most of the proteins on our site.

    Function Related Protein
    lipid transporter activity APOA1A; MTP; RFT1; APOA2; CETP; VTG2; APOC4; APOF; APOE; MTTP

    APOC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of APOC4.

    Hu, MA; Lui, SSH; et al. Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients. PHARMACOGENETICS AND GENOMICS 20:634-637(2010).
    Kim, E; Li, K; et al. Expression of apolipoprotein C-IV is regulated by Ku antigen/peroxisome proliferator-activated receptor gamma complex and correlates with liver steatosis. JOURNAL OF HEPATOLOGY 49:787-798(2008).

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