ARHGAP28
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Official Full Name
Rho GTPase activating protein 28
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Synonyms
ARHGAP28; Rho GTPase activating protein 28; rho GTPase-activating protein 28; FLJ10312; KIAA1314; Rho type GTPase activating protein 28; rho-type GTPase-activating protein 28;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ARHGAP28-768H | Recombinant Human ARHGAP28 protein, GST-tagged | Wheat Germ | GST | ||
Human | ARHGAP28-112HCL | Recombinant Human ARHGAP28 cell lysate | N/A | |||
Human | ARHGAP28-2950H | Recombinant Human ARHGAP28 protein, His-tagged | E.coli | His | 1-167 aa | |
Human | ARHGAP28-1323HF | Recombinant Full Length Human ARHGAP28 Protein, GST-tagged | In Vitro Cell Free System | GST | 545 amino acids | |
Mouse | ARHGAP28-1867M | Recombinant Mouse ARHGAP28 Protein | Mammalian Cell | His | ||
Mouse | ARHGAP28-677M | Recombinant Mouse ARHGAP28 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ARHGAP28-677M-B | Recombinant Mouse ARHGAP28 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | ARHGAP28-1813Z | Recombinant Zebrafish ARHGAP28 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
ARHGAP28 involved in several pathways and played different roles in them. We selected most pathways ARHGAP28 participated on our site, such as Rho GTPase cycle, Signal Transduction, Signaling by Rho GTPases, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Rho GTPase cycle | FGD2;ARHGAP29;ARHGAP10;DEPDC7;ARHGAP29B;ECT2;RHOJ;DCLRE1B;CHN2 |
Signal Transduction | MYO7A;PENK;STARD8;WLS;MKL1B;RGS1;STARD13;BBS13;RBP4 |
Signaling by Rho GTPases | ARHGAP12B;TAGAP;RHOUA;ARHGAP23;ARHGAP1;FAM13A;ARHGAP32;ARHGAP4A;FMNL2 |
ARHGAP28 has several biochemical functions, for example, GTPase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP28 itself. We selected most functions ARHGAP28 had, and list some proteins which have the same functions with ARHGAP28. You can find most of the proteins on our site.
Function | Related Protein |
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GTPase activator activity | ARHGAP40;RAP1GAP2A;GIT2;RGS12B;RAP1GAP;ARHGAP6;STARD8;PLCB1;ARHGAP36 |
ARHGAP28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP28 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP28.
HSPB1
- Q&As
- Reviews
Q&As (12)
Ask a questionYes, ARHGAP28 has been shown to interact with several proteins involved in Rho GTPase signaling pathways. For example, it can interact with RhoA, Rac1, and Cdc42, suggesting its role in modulating their activities.
It is advisable to consult scientific databases or literature repositories to stay updated on any ongoing research studies or recent publications related to ARHGAP28. These sources will provide accurate and current information on the latest findings regarding ARHGAP28 and its functions.
To the best of my knowledge, there are currently no specific animal models that have been developed to study ARHGAP28. However, researchers may potentially utilize gene knockout or knockdown techniques to study its function in animal models.
Currently, there is no evidence to suggest that ARHGAP28 can be used as a diagnostic or prognostic marker for any diseases. It is important to conduct further research to explore its potential clinical relevance.
ARHGAP28 is widely expressed across different tissues in the body. It has been detected in various cell types, including neurons, epithelial cells, and immune cells.
There is limited information on the involvement of ARHGAP28 in cell migration or invasion. However, given its association with Rho GTPases, which are key regulators of these processes, ARHGAP28 may potentially play a role in cell migration and invasion.
Currently, there are no specific studies linking ARHGAP28 to particular diseases or conditions. Thus, more research is needed to determine its potential involvement in different physiological and pathological processes.
ARHGAP28 has been shown to interact with proteins involved in the Rho GTPase signaling pathway. Additionally, it may localize to cellular structures such as actin-rich filopodia and lamellipodia, which play key roles in cell movement and adhesion.
Currently, there are no known genetic variations or mutations in the ARHGAP28 gene associated with diseases. Further studies are needed to determine if any genetic alterations in this gene have implications for human health.
ARHGAP28 is believed to function as a negative regulator of Rho GTPases, which are involved in several signaling pathways, including those related to actin cytoskeleton organization, cell adhesion, and cell migration. Therefore, ARHGAP28 may indirectly influence these signaling pathways through its modulation of Rho GTPases.
As of now, there are no known drugs or inhibitors specifically targeting ARHGAP28. Further exploration of its function and potential therapeutic implications may reveal novel possibilities for targeted interventions.
There is currently limited information on the relationship between ARHGAP28 and developmental disorders. However, given its involvement in cell motility and morphology, it is plausible that disruptions in ARHGAP28 expression or function could contribute to developmental abnormalities, but more research is needed to establish such connections.
Customer Reviews (10)
Write a reviewI have full confidence in the ARHGAP28 protein and the exceptional support provided by the manufacturer, making it my top recommendation for researchers seeking a high-quality protein for their experimental needs.
Their knowledgeable team has been readily available to address any concerns or queries, providing effective solutions and guidance whenever needed.
Its integrity and reliability make it an ideal choice to address the specific objectives of my research.
I am extremely pleased with the quality of the ARHGAP28 protein as it perfectly fulfills my experimental requirements.
Their ability to accommodate the requirements of large-scale experiments and guarantee a steady supply streamlines my research operations, eliminating any concerns related to prospective shortages.
I am delighted to express my complete satisfaction with the quality of ARHGAP28 protein, as it precisely suits my experimental requirements.
This protein exhibits exceptional purity and reliability, ensuring accurate and reproducible results in my assays.
With their meticulous documentation and support, I am confident that my utilization of the ARHGAP8 protein in clinical trials will meet all necessary regulations and guidelines.
Their comprehensive certificates of analysis and safety data sheets serve as testaments to their commitment to ensuring the safety and integrity of their products.
In addition to the exceptional quality of the protein, the manufacturer's support extends beyond the product itself.
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