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Recombinant Human ARHGAP28 protein, GST-tagged

Cat.No. : ARHGAP28-768H
Product Overview : Human ARHGAP28 full-length ORF ( AAH65274.1, 1 a.a. - 545 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : ARHGAP28 (Rho GTPase Activating Protein 28) is a Protein Coding gene. Diseases associated with ARHGAP28 include Benign Meningioma and Central Nervous System Organ Benign Neoplasm. Among its related pathways are Signaling by GPCR and p75 NTR receptor-mediated signalling. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP18.
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 88.4 kDa
AA Sequence : MNELPRDTCGNHTNQLDGTKEEREL PRVIKTSGSMPDDASLNSTTLSDAS QDKEGSFAVPRSDSVAILETIPVLP VHSNGSPEPGQPVQNAISDDDFLEK NIPPEAEELSFEVSYSEMVTEALKR NKLKKSEIKKEDYVLTKFNVQKTRF GLTEAGDLSAEDMKKIRHLSLIELT AFFDAFGIQLKRNKTEKVKGRDNGI FGVPLTVLLDGDRKKDPGVKVPLVL QKFFEKVEESGLESEGIFRLSGCTA KVKQYREELDAKFNADKFKWDKMCH REAAVMLKAFFRELPTSLFPVEYIP AFISLMERGPHVKVQFQALHLMVMA LPDANRDAAQALMTFFNKVIANESK NRMSLWNISTVMAPNLFFSRSKHSD YEELLLANTAAHIIRLMLKYQKILW KVPSFLITQVRRMNEATMLLKKQLP SVRKLLRRKTLERETASPKTSKVLQ KSPSARRMSDVPEGVIRVHAPLLSK VSMAIQLNNQTKAKDILAKFQYENR ILHWQRAALSFLNGKWVKKEREEST ETNRSPKHVFLFTIGLDIST
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ARHGAP28 Rho GTPase activating protein 28 [ Homo sapiens ]
Official Symbol : ARHGAP28
Synonyms : ARHGAP28; Rho GTPase activating protein 28; rho GTPase-activating protein 28; FLJ10312; KIAA1314; rho-type GTPase-activating protein 28; FLJ27160; DKFZp686A2038;
Gene ID : 79822
mRNA Refseq : NM_001010000
Protein Refseq : NP_001010000
MIM : 610592
UniProt ID : Q9P2N2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (12)

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Can ARHGAP28 interact with other proteins? 10/24/2022

Yes, ARHGAP28 has been shown to interact with several proteins involved in Rho GTPase signaling pathways. For example, it can interact with RhoA, Rac1, and Cdc42, suggesting its role in modulating their activities.

Are there any ongoing research studies or recent publications related to ARHGAP28? 12/09/2021

It is advisable to consult scientific databases or literature repositories to stay updated on any ongoing research studies or recent publications related to ARHGAP28. These sources will provide accurate and current information on the latest findings regarding ARHGAP28 and its functions.

Are there any animal models available for studying ARHGAP28? 12/08/2021

To the best of my knowledge, there are currently no specific animal models that have been developed to study ARHGAP28. However, researchers may potentially utilize gene knockout or knockdown techniques to study its function in animal models.

Can ARHGAP28 be used as a diagnostic or prognostic marker for any diseases? 09/17/2021

Currently, there is no evidence to suggest that ARHGAP28 can be used as a diagnostic or prognostic marker for any diseases. It is important to conduct further research to explore its potential clinical relevance.

Is ARHGAP28 expressed in all tissues or is it tissue-specific? 02/25/2021

ARHGAP28 is widely expressed across different tissues in the body. It has been detected in various cell types, including neurons, epithelial cells, and immune cells.

Is ARHGAP28 involved in cell migration or invasion? 01/01/2021

There is limited information on the involvement of ARHGAP28 in cell migration or invasion. However, given its association with Rho GTPases, which are key regulators of these processes, ARHGAP28 may potentially play a role in cell migration and invasion.

Are there any studies linking ARHGAP28 to specific diseases or conditions? 12/10/2020

Currently, there are no specific studies linking ARHGAP28 to particular diseases or conditions. Thus, more research is needed to determine its potential involvement in different physiological and pathological processes.

Is ARHGAP28 associated with any other proteins or cellular structures? 09/10/2020

ARHGAP28 has been shown to interact with proteins involved in the Rho GTPase signaling pathway. Additionally, it may localize to cellular structures such as actin-rich filopodia and lamellipodia, which play key roles in cell movement and adhesion.

Are there any genetic variations or mutations in the ARHGAP28 gene associated with diseases? 03/11/2020

Currently, there are no known genetic variations or mutations in the ARHGAP28 gene associated with diseases. Further studies are needed to determine if any genetic alterations in this gene have implications for human health.

Is ARHGAP28 associated with any signaling pathways? 01/05/2020

ARHGAP28 is believed to function as a negative regulator of Rho GTPases, which are involved in several signaling pathways, including those related to actin cytoskeleton organization, cell adhesion, and cell migration. Therefore, ARHGAP28 may indirectly influence these signaling pathways through its modulation of Rho GTPases.

Are there any known drugs or inhibitors that specifically target ARHGAP28? 10/22/2016

As of now, there are no known drugs or inhibitors specifically targeting ARHGAP28. Further exploration of its function and potential therapeutic implications may reveal novel possibilities for targeted interventions.

Can disruptions in ARHGAP28 expression or function lead to developmental disorders? 04/18/2016

There is currently limited information on the relationship between ARHGAP28 and developmental disorders. However, given its involvement in cell motility and morphology, it is plausible that disruptions in ARHGAP28 expression or function could contribute to developmental abnormalities, but more research is needed to establish such connections.

Customer Reviews (10)

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Reviews
10/28/2022

    I have full confidence in the ARHGAP28 protein and the exceptional support provided by the manufacturer, making it my top recommendation for researchers seeking a high-quality protein for their experimental needs.

    06/30/2022

      Their knowledgeable team has been readily available to address any concerns or queries, providing effective solutions and guidance whenever needed.

      01/07/2021

        Its integrity and reliability make it an ideal choice to address the specific objectives of my research.

        04/24/2020

          I am extremely pleased with the quality of the ARHGAP28 protein as it perfectly fulfills my experimental requirements.

          03/31/2020

            Their ability to accommodate the requirements of large-scale experiments and guarantee a steady supply streamlines my research operations, eliminating any concerns related to prospective shortages.

            10/10/2018

              I am delighted to express my complete satisfaction with the quality of ARHGAP28 protein, as it precisely suits my experimental requirements.

              10/24/2016

                This protein exhibits exceptional purity and reliability, ensuring accurate and reproducible results in my assays.

                08/27/2016

                  With their meticulous documentation and support, I am confident that my utilization of the ARHGAP8 protein in clinical trials will meet all necessary regulations and guidelines.

                  08/25/2016

                    Their comprehensive certificates of analysis and safety data sheets serve as testaments to their commitment to ensuring the safety and integrity of their products.

                    05/03/2016

                      In addition to the exceptional quality of the protein, the manufacturer's support extends beyond the product itself.

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