ATOX1
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Official Full Name
ATX1 antioxidant protein 1 homolog (yeast)
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Overview
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. -
Synonyms
ATOX1; ATX1 antioxidant protein 1 homolog (yeast); ATX1 (antioxidant protein 1, yeast) homolog 1; copper transport protein ATOX1; HAH1; Antioxidant protein 1; ATOX1_HUMAN; ATX1; ATX1 (antioxidant protein 1 yeast) homolog 1; ATX1 antioxidant protein 1 homolog; Copper transport protein; Metal transport protein; Metal transport protein ATX1; MGC138453; MGC138455; OTTHUMP00000224114; OTTHUMP00000224178;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- E.Coli or Yeast
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
ATOX1 involved in several pathways and played different roles in them. We selected most pathways ATOX1 participated on our site, such as Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATOX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mineral absorption | MT1H;TF;SLC9A3;CYBRD1;MT2;SLC26A3;MT1F;MT1E;SLC31A1 |
ATOX1 has several biochemical functions, for example, copper chaperone activity, copper ion binding, copper ion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATOX1 itself. We selected most functions ATOX1 had, and list some proteins which have the same functions with ATOX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| copper chaperone activity | COX17;ATOX1;ATX1 |
| copper ion binding | P2RX2;ANG;S100A12;ATP7B;LOXL4;HAMP;TP53;SLC11A2;TRP53 |
| copper ion transmembrane transporter activity | ATOX1;SLC31A1;MMGT2;SLC31A2;SLC11A2;ATP7A |
| copper-dependent protein binding | FKBP4;ATP7A;ATOX1 |
| metallochaperone activity | |
| protein binding | ZNF193;ABCD3;MIS12;CEBPB;CCDC167;TRIM15;TOMM22;RBPJ;FKBPL |
ATOX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATOX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATOX1.
C21orf2; GGPS1; FAM118A
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