ATP1B4

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ATP1B4

Official Full Name ATPase, Na+/K+ transporting, beta 4 polypeptide
Background This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms ATP1B4; ATPase, Na+/K+ transporting, beta 4 polypeptide; ATPase, (Na+)/K+ transporting, beta 4 polypeptide; protein ATP1B4; X,K-ATPase beta-m subunit; x/potassium-transporting ATPase subunit beta-m
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • T7
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Atp1b4-1765M Recombinant Mouse Atp1b4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human ATP1B4-3984H Recombinant Human ATP1B4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ATP1B4-2941H Recombinant Human ATP1B4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ATP1B4-48HCL Recombinant Human ATP1B4 lysate HEK293 N/A
    Human ATP1B4-968H Recombinant Human ATP1B4 protein Wheat Germ N/A
    Mouse ATP1B4-2119M Recombinant Mouse ATP1B4 Protein Mammalian Cell His
    Rat ATP1B4-1535R Recombinant Rat ATP1B4 protein, His & T7-tagged E.coli His/T7
    Rat ATP1B4-858R Recombinant Rat ATP1B4 Protein Mammalian Cell His
    Chicken ATP1B4-3443C Recombinant Chicken ATP1B4 Mammalian Cell His

    ATP1B4 involved in several pathways and played different roles in them. We selected most pathways ATP1B4 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP1B4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cGMP-PKG signaling pathway LOC100328615; AGTR1A; ROCK1; NPPB; CALM3; PDE5A; MEF2D; PDE3B; SLC25A5; VDAC3
    cAMP signaling pathway PDE4B; MAPK1; RAF1; MLLT4; HCN2; RRAS2; DRD1A; GRIN2D; ATP2B4; FXYD2
    Cardiac muscle contraction ATP1B2; CACNA1SA; COX6B2; MYL2; CACNB4A; ATP1A4; UQCRC1; ATP1B3A; CACNG8; MYL2B
    Adrenergic signaling in cardiomyocytes CAMK2D1; CACNB4; CACNA1D; BCL2; MAPK3; SLC8A1; ATP1B3A; GNAI2; PPP1CC; ATP1B2
    Insulin secretion GNAS; KCNMB4; STX1A; KCNN2; PRKACB; GNAQ; TRPM4; ATF4; PLCB3; PRKACG
    Thyroid hormone synthesis PRKACG; TTF2; DUOX2; GPX6; TSHB; IYD; PRKACA; ATF4; PRKCB; PDIA4
    Thyroid hormone signaling pathway MED17; PLN; PLCD4; PIK3CB; ITGAV; ATP1A3; TSC2; CASP9; HDAC1; PLCG2
    Aldosterone-regulated sodium reabsorption MAPK3; ATP1A1; PIK3R2; NEDD4L; ATP1A3; PRKCG; ATP1B3; IGF1; IRS1; PIK3R3
    Endocrine and other factor-regulated calcium reabsorption PLCB4; ATP1A1; KLK1B5; CALB1; KL; VDR; ESR1; ATP1A4; PLCB1; PRKACB
    Proximal tubule bicarbonate reclamation SLC25A10; Car2; ATP1A4; CA2; ATP1A1; ATP1B4; SLC4A4; ATP1B2; SLC38A3; Car4
    Salivary secretion CALML5; GUCY1A3; PRB1; PRKACB; CAMP; RYR3; ATP1A2; PLCB4; STATH; CST5
    Gastric acid secretion GNAI1; GNAS; KCNJ15; KCNJ2; KCNQ1; KCNJ1; ITPR1; ATP4A; GNAI3; KCNK10
    Pancreatic secretion GNAS; CELA2A; PLA2G2D; PRSS1; AMY2A4; CPA3; ITPR1; CCKAR; CA2; CLCA5
    Carbohydrate digestion and absorption SI; ATP1B1; AMY2B; SLC2A5; Amy1; TAS1R2; PLCB2; ATP1A3; ATP1A4; ATP1A2
    Protein digestion and absorption COL24A1; COL7A1; MME; PRSS3; ATP1B3; COL4A1; SLC7A8; KCNQ1; CELA3A; DPP4
    Bile secretion ATP1A4; AQP4; SLCO1A2; HMGCR; ABCB1; LDLR; ABCB1A; OSTB; ADCY8; ATP1B2
    Mineral absorption FXYD2; TF; SLC11A2; SLC26A9; VDR; SLC40A1; ATP1A2; MT1H; SLC34A2; MT1M

    ATP1B4 has several biochemical functions, for example, monovalent inorganic cation transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP1B4 itself. We selected most functions ATP1B4 had, and list some proteins which have the same functions with ATP1B4. You can find most of the proteins on our site.

    Function Related Protein
    monovalent inorganic cation transmembrane transporter activity ATP1B4

    ATP1B4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP1B4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP1B4.

    Gao, K; Song, Z; et al. Genetic analysis of the ATP1B4 gene in Chinese Han patients with Parkinson's disease. MOLECULAR BIOLOGY REPORTS 41:2307-2311(2014).
    Sarkozy, M; Zvara, A; et al. Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats. CARDIOVASCULAR DIABETOLOGY 12:-(2013).

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