atp1b4
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  • Official Full Name
  • ATPase, Na+/K+ transporting, beta 4 polypeptide
  • Background
  • This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • ATP1B4; ATPase, Na+/K+ transporting, beta 4 polypeptide; ATPase, (Na+)/K+ transporting, beta 4 polypeptide; protein ATP1B4; X,K-ATPase beta-m subunit; x/potassium-transporting ATPase subunit beta-m
Cat.#:ATP1B4-2941HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ATP1B4 Protein, MYC/DDK-tagged
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Cat.#:ATP1B4-968HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ATP1B4 protein
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Cat.#:ATP1B4-2119MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ATP1B4 Protein
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Cat.#:ATP1B4-1535RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat ATP1B4 protein, His & T7-tagged
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Cat.#:ATP1B4-858RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ATP1B4 Protein
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Cat.#:ATP1B4-3443CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ATP1B4
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Cat.#:ATP1B4-48HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ATP1B4 lysate
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Involved Pathway

ATP1B4 involved in several pathways and played different roles in them. We selected most pathways ATP1B4 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP1B4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
cGMP-PKG signaling pathway
VDAC2; PLCB1; BDKRB2; ATP2B4; ATP2B1; PDE3A; IRS4; GNAI1; PPP3R1; PRKG2
cAMP signaling pathway
GRIN2D; GLI3; PLN; PRKACB; NPY1R; MAPK10; GPR81; GLI1; ATP1A1; PIK3CB
Cardiac muscle contraction
COX7A2A; COX7A3; MYL3; COX4I2; TPM1; ATP1A3B; TNNI3; ATP1A4; CACNA1D; CACNA1SB
Adrenergic signaling in cardiomyocytes
CALM2B; PPP2R5A; PPP2R5D; TNNT2A; FXYD2; PPP2R2D; SLC14A2; CREB3L2; NETO2; MAPK14
Insulin secretion
ATP1A4; GNAQ; CCKAR; GCG; PLCB3; Adcy4; PCLO; PRKCG; SLC2A1; PRKCA
Thyroid hormone synthesis
ATP1B1; TSHR; ATF4; HSP90B1; Adcy4; PDIA4; ITPR1; PLCB2; PLCB1; ATP1B3
Thyroid hormone signaling pathway
ATP1B1; RAF1; ATP1B2; ATP1B3; FOXO1; GSK3B; ATP1B4; HDAC1; RXRB; PLCG1
Aldosterone-regulated sodium reabsorption
ATP1A1; PIK3CG; ATP1B3; ATP1A2; IRS1; ATP1B1; PIK3R5; KRAS; KCNJ1; IGF1
Endocrine and other factor-regulated calcium reabsorption
VDR; ATP1B1; SLC8A1; KLK1B24; RAB11A; CALB1; KLK1B8; FXYD2; KLK1B5; ATP2B1
Proximal tubule bicarbonate reclamation
SLC25A10; GLS2; ATP1B4; ATP1B2; FXYD2; CA2; GLS; GLUD2; PCK2; ATP1B1
Salivary secretion
PRKG1; VAMP2; CST3; AMY1B; LYZ; GUCY1A3; DMBT1; CALM2; BEST2; PLCB1
Gastric acid secretion
KCNJ15; MYLK3; SLC9A4; CALML5; CALML3; ATP4B; ACTB; KCNJ2; PRKACA; Adcy4
Pancreatic secretion
PLA2G2E; GNAQ; RHOA; PLA2G12B; PRKCG; PLA2G2D; TRPC1; RAC1; CPA3; PNLIP
Carbohydrate digestion and absorption
FXYD2; HKDC1; AKT1; PIK3CD; AMY2A3; ATP1A2; ATP1A3; PIK3CB; G6PC; HK2
Protein digestion and absorption
ATP1A3; CELA3A; COL24A1; SLC3A2; PGA4; SLC8A2; SLC1A1; PRSS1; COL4A1; COL7A1
Bile secretion
ATP1B1; FXYD2; PRKACG; CYP7A1; EPHX1; ATP1B3; ABCC3; ABCB1A; CYP3A4; SCARB1
Mineral absorption
TF; ATP1A3; MT1F; HEPH; ATP1B4; CLCN2; MT1A; MT1G; STEAP1; SLC11A1

Protein Function

ATP1B4 has several biochemical functions, for example, monovalent inorganic cation transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP1B4 itself. We selected most functions ATP1B4 had, and list some proteins which have the same functions with ATP1B4. You can find most of the proteins on our site.
Function
Related Protein
Function monovalent inorganic cation transmembrane transporter activity
Related Protein ATP1B4

ATP1B4 Related Articles

Gao, K; Song, Z; et al. Genetic analysis of the ATP1B4 gene in Chinese Han patients with Parkinson's disease. MOLECULAR BIOLOGY REPORTS 41:2307-2311(2014).
Sarkozy, M; Zvara, A; et al. Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats. CARDIOVASCULAR DIABETOLOGY 12:-(2013).