ATP1B4 Protein, ATPase, Na+/K+ transporting, beta 4 polypeptide


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Official Full Name ATPase, Na+/K+ transporting, beta 4 polypeptide
Background This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms ATP1B4; ATPase, Na+/K+ transporting, beta 4 polypeptide; ATPase, (Na+)/K+ transporting, beta 4 polypeptide; protein ATP1B4; X,K-ATPase beta-m subunit; x/potassium-transporting ATPase subunit beta-m
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • T7
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATP1B4-2941H Recombinant Human ATP1B4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ATP1B4-48HCL Recombinant Human ATP1B4 lysate HEK293 N/A
    Human ATP1B4-968H Recombinant Human ATP1B4 protein Wheat Germ N/A
    Mouse ATP1B4-2119M Recombinant Mouse ATP1B4 Protein Mammalian Cell His
    Rat ATP1B4-1535R Recombinant Rat ATP1B4 protein, His & T7-tagged E.coli His/T7
    Rat ATP1B4-858R Recombinant Rat ATP1B4 Protein Mammalian Cell His
    Chicken ATP1B4-3443C Recombinant Chicken ATP1B4 Mammalian Cell His

    ATP1B4 involved in several pathways and played different roles in them. We selected most pathways ATP1B4 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP1B4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cGMP-PKG signaling pathway PIK3CG; NOS3; TRPC6; NPPB; IRS4; ATP2A1; INSR; ATP1A2; MEF2B; IRS1
    cAMP signaling pathway PLD2; NPR1; NFKB1; SLC9A1; LIPE; PIK3CA; CAMK2G; GRIN2B; FXYD1; PRKACB
    Cardiac muscle contraction CACNG7; UQCRB; TPM2; COX6A2; TNNT2; COX6C; CACNG3; COX7A2L; MYL3; MYH7
    Adrenergic signaling in cardiomyocytes MYL2; CREB3L4; CACNG2; AGTR1B; CREB5; MAPK13; TPM1; CACNB4; ATP2B1; PPP2R5A
    Insulin secretion PRKCG; INS1; KCNMB2; RAB3A; ATP1B1; GNAQ; PRKACG; PRKACB; ATP1A3; RYR2
    Thyroid hormone synthesis DUOX2; PLCB1; FXYD2; ATP1B2; TSHR; TG; GPX2; ITPR3; ITPR1; HSPA5
    Thyroid hormone signaling pathway HDAC1; HRAS; ATP1B3; PLCB1; PIK3CD; THRA; MED13L; NOTCH3; SLC9A1; RXRG
    Aldosterone-regulated sodium reabsorption SFN; NR3C2; ATP1B3; PIK3CD; KCNJ1; FXYD4; ATP1B4; KRAS; MAPK3; ATP1B1
    Endocrine and other factor-regulated calcium reabsorption ESR1; PLCB1; KLK1B22; CALB1; VDR; ATP1B4; PRKCA; ATP1B2; ATP1B1; ATP1B3
    Proximal tubule bicarbonate reclamation SLC25A10; ATP1A3; FXYD2; PCK1; CA4; CA2; ATP1B4; SLC9A3; Car4; SLC38A3
    Salivary secretion TRPV6; CST4; CALM4; AMY1A; MUC5B; LYZ1; PLCB2; BST1; PMAP-36; SLC9A1
    Gastric acid secretion KCNE2; PRKACB; ITPR1; PRKCA; GAST; KCNJ2; GNAI1; CA2; SLC9A4; ACTB
    Pancreatic secretion Car2; ATP1A2; PRKCA; RAB3D; PRSS2; CPA2; PLA2G1B; CPA1; GNAQ; CELA2B
    Carbohydrate digestion and absorption SLC5A1; G6PC; AKT2; AMY1A; FXYD2; AMY1B; ATP1B3; HK1; PRKCB; PIK3R5
    Protein digestion and absorption COL7A1; COL24A1; MEP1B; PRCP; SLC1A1; COL18A1; SLC1A5; ATP1B2; ATP1B1; XPNPEP2
    Bile secretion ABCG2; RXRA; Adcy4; Slc4a2; NR1H4; SLC10A2; ATP1B2; SCTR; KCNN2; ATP1B4
    Mineral absorption ATP7A; SLC30A1; MT1A; ATP1B1; TRPV6; CYBRD1; SLC26A6; FXYD2; ATP1A2; MT1G

    ATP1B4 has several biochemical functions, for example, monovalent inorganic cation transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP1B4 itself. We selected most functions ATP1B4 had, and list some proteins which have the same functions with ATP1B4. You can find most of the proteins on our site.

    Function Related Protein
    monovalent inorganic cation transmembrane transporter activity ATP1B4

    ATP1B4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP1B4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP1B4.

    Gao, K; Song, Z; et al. Genetic analysis of the ATP1B4 gene in Chinese Han patients with Parkinson's disease. MOLECULAR BIOLOGY REPORTS 41:2307-2311(2014).
    Sarkozy, M; Zvara, A; et al. Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats. CARDIOVASCULAR DIABETOLOGY 12:-(2013).

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