ATP2A2

  • Official Full Name

    ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
  • Synonyms

    Serca2;SercaII

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Rat
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • HeLa
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
ATP2A2-2585H Recombinant Human ATP2A2, His-tagged E.coli Human His 320-700aa
ATP2A2-2684H Recombinant Human ATP2A2 protein, His-tagged E.coli Human His 314-580 aa
ATP2A2-463H Recombinant Human ATP2A2 Protein, His/GST-tagged E.coli Human GST&His Ile315~Met756
ATP2A2-2121M Recombinant Mouse ATP2A2 Protein Mammalian Cells Mouse His
ATP2A2-4692C Recombinant Chicken ATP2A2 Mammalian Cells Chicken His
ATP2A2-4693C Recombinant Chicken ATP2A2 Mammalian Cells Chicken His
ATP2A2-859R Recombinant Rat ATP2A2 Protein Mammalian Cells Rat His
ATP2A2-970H Recombinant Human ATP2A2 protein, GST-tagged Wheat Germ Human GST
ATP2A2-8609HCL Recombinant Human ATP2A2 293 Cell Lysate HEK293 Human Non
ATP2A2-062HKCL Human ATP2A2 Knockdown Cell Lysate HeLa Human Non
ATP2A2-1245HF Recombinant Full Length Human ATP2A2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 997 amino acids
ATP2A2-2565H Recombinant Human ATP2A2 protein, His-tagged E.coli Human His 314-756aa
ATP2A2-266H Recombinant Human ATP2A2 Protein, His-tagged E.coli Human His Ile315-Met756
ATP2A2-515R Recombinant Rat ATP2A2 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
ATP2A2-515R-B Recombinant Rat ATP2A2 Protein Pre-coupled Magnetic Beads HEK293 Rat
ATP2A2-855M Recombinant Mouse ATP2A2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ATP2A2-855M-B Recombinant Mouse ATP2A2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ATP2A2 involved in several pathways and played different roles in them. We selected most pathways ATP2A2 participated on our site, such as Calcium signaling pathway,cGMP-PKG signaling pathway,cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP2A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Alzheimers disease NDUFS1,NCSTN,ATP5O,UQCRH,NDUFA8,NDUFS4,GRIN2A,NDUFC1,COX5A,PLCB3
    Cardiac muscle contraction CACNA1SB,ATP1A1,UQCR10,CACNG4,COX7B,CACNG1,CACNA2D4,CACNG6,COX7A2L,CACNG3
    Dilated cardiomyopathy ITGA3,SGCA,ITGAV,ITGB3,ACTC1,SLC8A1,SGCB,RYR2,ITGB4,ACTG1
    Hypertrophic cardiomyopathy (HCM) TTN,ACTB,IGF1,CACNA2D4,SGCG,TGFB1,PRKAG2,LMNA,TGFB2,TNNI3
    cAMP signaling pathway NFKBIA,GNAI3,FXYD1,ATP1A1,GRIN1,ATP1B4,OXTR,PRKACB,CREB3L1,PDE3B
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) TCF7,SGCD,DSP,ITGA2B,CACNG1,SGCB,ACTN1,CTNNA2,ACTN2,CACNG4
    Pancreatic secretion CLCA1,CTRL,CPB2,GNAS,Slc4a2,PLA2G2F,CLCA4,ATP2A1,TRPC1,ATP2B4
    Thyroid hormone signaling pathway PIK3CD,ACTB,NRAS,ATP1B1,PLCE1,PRKACA,MED13,HDAC2,PLN,MED4
    Adrenergic signaling in cardiomyocytes RAPGEF3,TPM4A,SLC14A2,CREB3L3L,CACNG6A,ADRA1BB,ATP2B2,GNAIA,PRKACA,GNA15.4

    Protein Function

    ATP2A2 has several biochemical functions, for example, ATP binding,S100 protein binding,calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP2A2 itself. We selected most functions ATP2A2 had, and list some proteins which have the same functions with ATP2A2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TSSK3,TBC1D17,SPAT-1,PLCE1,MED31,PPP4C,DYRK4,DHX15,ADAP1,MEN1
    protein C-terminus binding BCL10,MAPRE1,CDC37,RBFOX1,TOP2A,DST,ERCC6,PPP1R9B,SHANK1,PIAS4
    S100 protein binding EZR,ANXA2,S100B,AGER,S100A6,AHNAK,S100A1,S100A11,KCNK3,ANXA11
    ATP binding ADCK1,ATP9B,PIK3CB,ATP6V1AA,GSK3AA,ATP13A3,MAP4K6,UBE2H,SMC2,PIP5K2
    enzyme binding ECM1,ANK1,RCOR1,DNM2,YWHAE,U2AF2,PUS7,TSPAN15,NOS1,H2AFX
    calcium ion binding NOTCH4,EEF2K,PCDH2AB3,SLC25A25A,PCDHGB4,CSN2,EFHA2,CABP5B,CALN1,PLA2G10
    calcium-transporting ATPase activity ATP2B1B,ATP2B3B,ATP2B3A,ATP2A2B,ATP2A1L,ATP2C1,ATP2B2,ATP2A2A,ATP2B1,ATP2B4

    Interacting Protein

    ATP2A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP2A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP2A2.

    MYC;OPRD1;EGFR;CANX;ILK;env;PTP4A3;TNF;TNFRSF1A;TNFRSF1B;TRADD;PPP5C;TRAF6

    Resources

    References

    • Powell, H; Affolter, VK; et al. Combined decongestive therapy including equine manual lymph drainage to assist management of chronic progressive lymphoedema in draught horses. EQUINE VETERINARY EDUCATION 24:81-89(2012).
    • Dally, S; Corvazier, E; et al. Multiple and diverse coexpression, location, and regulation of additional SERCA2 and SERCA3 isoforms in nonfailing and failing human heart. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 48:633-644(2010).

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