ATP2A2
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Official Full Name
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -
Synonyms
Serca2;SercaII
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rat
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- HeLa
- In Vitro Cell Free System
- His
- GST
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ATP2A2-2585H | Recombinant Human ATP2A2, His-tagged | E.coli | Human | His | 320-700aa | |
| ATP2A2-2684H | Recombinant Human ATP2A2 protein, His-tagged | E.coli | Human | His | 314-580 aa | |
| ATP2A2-463H | Recombinant Human ATP2A2 Protein, His/GST-tagged | E.coli | Human | GST&His | Ile315~Met756 | |
| ATP2A2-2121M | Recombinant Mouse ATP2A2 Protein | Mammalian Cells | Mouse | His |
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| ATP2A2-4692C | Recombinant Chicken ATP2A2 | Mammalian Cells | Chicken | His |
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| ATP2A2-4693C | Recombinant Chicken ATP2A2 | Mammalian Cells | Chicken | His |
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| ATP2A2-859R | Recombinant Rat ATP2A2 Protein | Mammalian Cells | Rat | His |
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| ATP2A2-970H | Recombinant Human ATP2A2 protein, GST-tagged | Wheat Germ | Human | GST |
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| ATP2A2-8609HCL | Recombinant Human ATP2A2 293 Cell Lysate | HEK293 | Human | Non |
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| ATP2A2-062HKCL | Human ATP2A2 Knockdown Cell Lysate | HeLa | Human | Non |
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| ATP2A2-1245HF | Recombinant Full Length Human ATP2A2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 997 amino acids |
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| ATP2A2-2565H | Recombinant Human ATP2A2 protein, His-tagged | E.coli | Human | His | 314-756aa |
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| ATP2A2-266H | Recombinant Human ATP2A2 Protein, His-tagged | E.coli | Human | His | Ile315-Met756 |
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| ATP2A2-515R | Recombinant Rat ATP2A2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| ATP2A2-515R-B | Recombinant Rat ATP2A2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ATP2A2-855M | Recombinant Mouse ATP2A2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ATP2A2-855M-B | Recombinant Mouse ATP2A2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ATP2A2 involved in several pathways and played different roles in them. We selected most pathways ATP2A2 participated on our site, such as Calcium signaling pathway,cGMP-PKG signaling pathway,cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP2A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Dilated cardiomyopathy | CACNG7,TPM1,CACNA2D3,TPM4,ITGB1,Adcy4,RYR2,ITGB7,SGCA,ACTG1 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | JUP,ITGA6,SGCA,RYR2,ITGA4,CACNB1,ACTB,Itga10&Itgb1,AASS,CACNG4 |
| cGMP-PKG signaling pathway | PPP3CC,PIK3CD,GTF2I,PDE3A,IRS2,PDE5A,CREB3L3,PPP1CB,MAP2K2,VDAC1 |
| Thyroid hormone signaling pathway | SIN3A,ITGB3,HDAC2,ACTB,WNT4,PFKP,PRKACB,HRAS,GSK3B,RXRG |
| Alzheimers disease | PPP3R2,MAPT,CAPN2,PLCB3,COX6C,ADAM10,APH1C,PLCB1,ATP5E,UQCR10 |
| Adrenergic signaling in cardiomyocytes | TMEM8C,MAPK14,ATP2B1,ADRA1BB,ADRA1B,PPP1CB,ATP1A1A.1,Adcy4,ADCY8,SCN1B |
| cAMP signaling pathway | PTGER2,GRIN2A,PRKACB,GRIN3B,PIK3R2,ATP1A3,ATP1B2,CALM4,GNAS,AMH |
| Hypertrophic cardiomyopathy (HCM) | ITGB6,CACNB4,CACNG7,PRKAG3,SGCA,TPM1,MYBPC3,CACNA2D4,ITGA5,CACNG4 |
| Cardiac muscle contraction | MYL4,CACNA2D2,COX7C,COX6B1,CACNA2D1A,ATP1B3B,TMEM8C,CACNB3A,TNNC1A,ATP1B1B |
Protein Function
ATP2A2 has several biochemical functions, for example, ATP binding,S100 protein binding,calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP2A2 itself. We selected most functions ATP2A2 had, and list some proteins which have the same functions with ATP2A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enzyme binding | TRIO,SLC12A3,PRKDC,DVL1,NLRP1,KPNB1,P4HB,CNTNAP2,RCOR3,CCND1 |
| calcium ion binding | CIB1,DAG1,CANX,AASS,CCDC47,CAPN9,PCDHA2,MAN1B1,ACTN2B,PCLO |
| ATP binding | PI4KA,PRPS1,ACTG1,RPS6KA3B,NEK7,SMARCA2,ACVRL1,GSK3AA,AK1,DGKA |
| S100 protein binding | ANXA11,EZR,FGF1A,KCNK3,S100B,AHNAK,FGF1,AGER,DDX1,S100A6 |
| calcium-transporting ATPase activity | ATP2B4,ATP2A1L,ATP2B1,ATP2B1A,ATP2A2A,ATP2B3A,ATP2A3,ATP2B1B,ATP2B3B,ATP2C1 |
| protein binding | ITM2C,MAD2L2,KIF9,C1QTNF1,TRIP13,KIAA0141,EBF1,EID3,NPM2,TUBA1A |
| protein C-terminus binding | CD2AP,PRKAA1,SHANK3,CTNNB1,HPCAL4,KSR1,SNTG1,VGLL2,FOXN3,ERCC6 |
Interacting Protein
ATP2A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP2A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP2A2.
MYC;OPRD1;EGFR;CANX;ILK;env;PTP4A3;TNF;TNFRSF1A;TNFRSF1B;TRADD;PPP5C;TRAF6
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References
- Powell, H; Affolter, VK; et al. Combined decongestive therapy including equine manual lymph drainage to assist management of chronic progressive lymphoedema in draught horses. EQUINE VETERINARY EDUCATION 24:81-89(2012).
- Dally, S; Corvazier, E; et al. Multiple and diverse coexpression, location, and regulation of additional SERCA2 and SERCA3 isoforms in nonfailing and failing human heart. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 48:633-644(2010).
