ATP2A2
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Official Full Name
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
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Synonyms
Serca2; SercaII;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian cell
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|GST
- N/A
- N
- 10×His
- Strep II
- Involved Pathway
- Protein Function
- Interacting Protein
- ATP2A2 Related Articles
ATP2A2 involved in several pathways and played different roles in them. We selected most pathways ATP2A2 participated on our site, such as Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP2A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Calcium signaling pathway | RYR1;MLCK2;GRPR;CAMK2D2;ATP2B1A;PHKG1;HTR5A;PRKACBA;ADORA2B |
cGMP-PKG signaling pathway | PIK3R5;CALM4;GNA11;INS2;MAP2K1;PLCB2;VDAC2;ATP1A1;PRKG2 |
cAMP signaling pathway | HTR1E;PRKACB;SLC9A1;PLD2;NPY;MAPK8;GABBR2;AMH;HTR6 |
Cardiac muscle contraction | CACNA2D1;COX7C;ATP1B3;CACNB3;CACNG1;CACNA2D3;SLC9A1;TPMA;FXYD2 |
Adrenergic signaling in cardiomyocytes | CACNA2D1;PIK3R3B;CACNG4;AKT2;CACNG2A;ATP2B3B;PRKACAB;CALM2A;SLC8A1 |
Thyroid hormone signaling pathway | PIK3CD;PRKCA;MED14;AKT2;ITGB3;DIO2;MAP2K2;AKT1;MED27 |
Pancreatic secretion | ITPR3;SLC4A4;ITPR1;KCNQ1;AMY2B;ATP1B4;ATP2B1;RAC1;RAB27B |
Alzheimers disease | ATF6;CDK5R1;ATP5F1;NDUFB5;NDUFB2;NDUFC2-KCTD14;GRIN1;COX8A;CAPN1 |
Hypertrophic cardiomyopathy (HCM) | TGFB2;TGFB1;PRKAG1;CACNG3;TNNC1;ITGA9;CACNG6;CACNA2D1;DES |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ITGB5;CACNB1;ITGB7;ITGA6;CACNG1;CACNA2D2;CACNB3;ITGA4;DMD |
Dilated cardiomyopathy | TTN;TPM3;ITGA6;CACNB1;Itga10&Itgb1;EMD;CACNB3;ITGB6;RYR2 |
ATP2A2 has several biochemical functions, for example, ATP binding, S100 protein binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP2A2 itself. We selected most functions ATP2A2 had, and list some proteins which have the same functions with ATP2A2. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | UCKL1;KIT;ACTB2;DDX47;NME2B.1;KIF18A;TYRO3;ACTR8;ERN1 |
S100 protein binding | KCNK3;DDX1;S100A1;ATP2A2;FGF1A;EZR;S100A6;AGER;S100A11 |
calcium ion binding | CDH24;NOTCH1B;PVALB4;CCDC48;GUCA1C;S100G;GUCA1D;PPP2R3A;EPDR1 |
calcium-transporting ATPase activity | ATP2C2;ATP2B1B;ATP2A2B;ATP2A2;ATP2B3A;ATP2B3B;ATP2B2;ATP2B1A;ATP2A3 |
calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential | |
enzyme binding | P4HB;CUTA;POR;NOTCH3;CTNNBL1;CNTNAP2;H2AFX;LYN;ACAT1 |
lutropin-choriogonadotropic hormone receptor binding | |
protein C-terminus binding | PABPC1;SDC1;PPP2CA;CTGF;MAPRE1;PCGF1;CEP135;MLLT4;TRP53 |
protein binding | SCYL3;GAS6;ARL8A;CD163;MPP6;MECP2;PARN;SLC1A2;SH2B3 |
ATP2A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP2A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP2A2.
MYC; OPRD1; EGFR; CANX; ILK; env; PTP4A3; TNF; TNFRSF1A; TNFRSF1B; TRADD; PPP5C; TRAF6
- Q&As
- Reviews
Q&As (6)
Ask a questionMutations in the recombinant ATP2A2 protein are associated with several nervous system related diseases, such as neurodegenerative diseases and neurodysregulation.
ATP2A2 protein is a calcium pump protein containing multiple membrane channels and ATP-binding sites for the regulation of intracellular calcium homeostasis.
Yes, the expression and function of ATP2A2 recombinant protein in the nervous system are regulated by complex mechanisms, including endogenous signaling pathways and cell-to-cell interactions.
Yes, there are polymorphic variations or mutations in ATP2A2 recombinant protein, which may be related to the susceptibility and pathogenesis of nervous system related diseases.
The recombinant ATP2A2 protein is responsible for regulating calcium homeostasis and maintaining nerve cell communication in the nervous system.
The recombinant ATP2A2 protein interacts with other membrane proteins, such as calcium channels and transporters, to regulate the function of nerve cells.
Customer Reviews (3)
Write a reviewBecause ATP2A2 has a short half-life and high clearance, it better prevents drug accumulation in the body, thereby reducing the risk of side effects caused by long-term use.
The production process of ATP2A2 focuses on harmonious coexistence with nature, realizes zero pollution in the production process, and brings a positive impact on the environment.
It can maintain stable performance even in extremely harsh environments, which is a rare quality.
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