Recombinant Human ATP2A2 protein, His-tagged

• Cat.No.: ATP2A2-2565H
• Product Overview: Recombinant Human ATP2A2 protein(P16615)(314-756aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
  If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 52.3 kDa
• Protein length: 314-756aa
• AA Sequence: VITTCLALGTRRMAKKNAIVRSLPS VETLGCTSVICSDKTGTLTTNQMSV CRMFILDRVEGDTCSLNEFTITGST YAPIGEVHKDDKPVNCHQYDGLVEL ATICALCNDSALDYNEAKGVYEKVG EATETALTCLVEKMNVFDTELKGLS KIERANACNSVIKQLMKKEFTLEFS RDRKSMSVYCTPNKPSRTSMSKMFV KGAPEGVIDRCTHIRVGSTKVPMTS GVKQKIMSVIREWGSGSDTLRCLAL ATHDNPLRREEMHLEDSANFIKYET NLTFVGCVGMLDPPRIEVASSVKLC RQAGIRVIMITGDNKGTAVAICRRI GIFGQDEDVTSKAFTGREFDELNPS AQRDACLNARCFARVEPSHKSKIVE FLQSFDEITAMTGDGVNDAPALKKA EIGIAMGSGTAVAKTASEMVLADDN FSTIVAAVEEGRAIYNNM
• Purity: Greater than 90% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.

Reviews

08/09/2020

Because ATP2A2 has a short half-life and high clearance, it better prevents drug accumulation in the body, thereby reducing the risk of side effects caused by long-term use.

07/28/2019

The production process of ATP2A2 focuses on harmonious coexistence with nature, realizes zero pollution in the production process, and brings a positive impact on the environment.

03/25/2019

It can maintain stable performance even in extremely harsh environments, which is a rare quality.

Q&As

Are ATP2A2 recombinant protein mutations associated with human nervous system related diseases?

Mutations in the recombinant ATP2A2 protein are associated with several nervous system related diseases, such as neurodegenerative diseases and neurodysregulation.

What are the structural features of the recombinant ATP2A2 protein?

ATP2A2 protein is a calcium pump protein containing multiple membrane channels and ATP-binding sites for the regulation of intracellular calcium homeostasis.

Is the expression and function of recombinant ATP2A2 protein regulated in the nervous system?

Yes, the expression and function of ATP2A2 recombinant protein in the nervous system are regulated by complex mechanisms, including endogenous signaling pathways and cell-to-cell interactions.

Is there any polymorphic variation or mutation in ATP2A2 recombinant protein?

Yes, there are polymorphic variations or mutations in ATP2A2 recombinant protein, which may be related to the susceptibility and pathogenesis of nervous system related diseases.

What is the function of ATP2A2 recombinant protein in the nervous system?

The recombinant ATP2A2 protein is responsible for regulating calcium homeostasis and maintaining nerve cell communication in the nervous system.

Does the recombinant ATP2A2 protein interact with other proteins?

The recombinant ATP2A2 protein interacts with other membrane proteins, such as calcium channels and transporters, to regulate the function of nerve cells.