|Official Full Name||ATPase, Ca++ transporting, type 2C, member 1|
|Background||The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.|
|Synonyms||ATP2C1; ATPase, Ca++ transporting, type 2C, member 1; BCPM, benign chronic pemphigus (Hailey Hailey disease); calcium-transporting ATPase type 2C member 1; ATP2C1A; KIAA1347; PMR1; secretory pathway Ca2+/Mn2+ ATPase 1; SPCA1; AW061228; D930003G21Rik; hSPCA1; OTTHUMP00000216069; OTTHUMP00000216071; OTTHUMP00000216072; OTTHUMP00000216073; OTTHUMP00000216074; 1700121J11Rik; AT2C1_HUMAN; ATP dependent Ca(2+) pump PMR1; ATP-dependent Ca(2+) pump PMR1; ATPase 2C1; BCPM; Calcium transporting ATPase type 2C member 1; HHD; HUSSY 28; MGC58010; MGC93231; OTTHUMP00000216066; OTTHUMP00000216068; OTTHUMP00000216075; PMR1L; SPCA; HUSSY-28; OTTHUMP00000216067; OTTHUMP00000216070|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ATP2C1 involved in several pathways and played different roles in them. We selected most pathways ATP2C1 participated on our site, such as Ion channel transport, Ion transport by P-type ATPases, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP2C1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Ion channel transport||BSND; Ano3; BEST3; WWP1; GLRBA; WNK2; TRPC5; CLCN4-2; TRPC4B; ATP1A1A.3|
|Ion transport by P-type ATPases||FXYD6; ATP11C; ATP13A5; ATP1A1A.2; ATP8B1; ATP13A; ATP1A1A.4; CCC2; ATP13A1; FXYD3|
|Transmembrane transport of small molecules||AQP8A.1; SLC24A4A; SLC22A7A; SLC38A3; FKBP1B; SLC29A1A; SLC22A18; SLC6A19B; SLC7A3A; SLC1A4|
ATP2C1 has several biochemical functions, for example, ATP binding, calcium ion binding, calcium-transporting ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP2C1 itself. We selected most functions ATP2C1 had, and list some proteins which have the same functions with ATP2C1. You can find most of the proteins on our site.
|ATP binding||GK; FARS2; NUAK2; ITPKC; ACSF3; PFTK1; INSRA; MAST2; EPHA4B; ABCB1A|
|calcium ion binding||GUCA1E; EFHA2; CRP; PCDHB1; CCDC167; AASS; ATP2C1; PCDHB11; SPTAN1; PKD2|
|calcium-transporting ATPase activity||ATP2B1B; ATP2B2; ATP2A1; ATP2B1A; ATP2B3A; ATP2B4; ATP2B1; ATP2B3B; ATP2A1L; ATP2C1|
|NOT calcium-transporting ATPase activity||ATP2C1|
|manganese ion binding||FEN1; DCP2; XPNPEP3; NUDT16; PPM1BA; HMGCL; PPM1M; SOD2; PPM1A; ME1|
|manganese-transporting ATPase activity||ATP2C1; ATP2C2|
|metal ion binding||SEMG2; CYP2AA2; RNF150A; CYP27C1; GNPTAB; BMPR1A; INSM2; PHF23B; FURIN; ARIH1L|
|signal transducer activity||OLFR149; BST2; GHRHR2; TAS2R123; OLFR146; OLFR502; PTGER1A; AGTR1B; GPR158; VMN1R50|
ATP2C1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP2C1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP2C1.