ATP2C1 Protein, ATPase, Ca++ transporting, type 2C, member 1


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Official Full Name ATPase, Ca++ transporting, type 2C, member 1
Background The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms ATP2C1; ATPase, Ca++ transporting, type 2C, member 1; BCPM, benign chronic pemphigus (Hailey Hailey disease); calcium-transporting ATPase type 2C member 1; ATP2C1A; KIAA1347; PMR1; secretory pathway Ca2+/Mn2+ ATPase 1; SPCA1; AW061228; D930003G21Rik; hSPCA1; OTTHUMP00000216069; OTTHUMP00000216071; OTTHUMP00000216072; OTTHUMP00000216073; OTTHUMP00000216074; 1700121J11Rik; AT2C1_HUMAN; ATP dependent Ca(2+) pump PMR1; ATP-dependent Ca(2+) pump PMR1; ATPase 2C1; BCPM; Calcium transporting ATPase type 2C member 1; HHD; HUSSY 28; MGC58010; MGC93231; OTTHUMP00000216066; OTTHUMP00000216068; OTTHUMP00000216075; PMR1L; SPCA; HUSSY-28; OTTHUMP00000216067; OTTHUMP00000216070
    • Species :
    • Human
    • Rhesus Macaque
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATP2C1-10012H Recombinant Human ATP2C1, His-tagged E.coli His
    Human ATP2C1-148HCL Recombinant Human ATP2C1 cell lysate N/A
    Human ATP2C1-974H Recombinant Human ATP2C1 protein, GST-tagged Wheat Germ GST
    Rhesus Macaque ATP2C1-452R Recombinant Rhesus monkey ATP2C1 Protein, His-tagged Mammalian Cell His

    ATP2C1 involved in several pathways and played different roles in them. We selected most pathways ATP2C1 participated on our site, such as Ion channel transport, Ion transport by P-type ATPases, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP2C1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ion channel transport BSND; Ano3; BEST3; WWP1; GLRBA; WNK2; TRPC5; CLCN4-2; TRPC4B; ATP1A1A.3
    Ion transport by P-type ATPases FXYD6; ATP11C; ATP13A5; ATP1A1A.2; ATP8B1; ATP13A; ATP1A1A.4; CCC2; ATP13A1; FXYD3
    Transmembrane transport of small molecules AQP8A.1; SLC24A4A; SLC22A7A; SLC38A3; FKBP1B; SLC29A1A; SLC22A18; SLC6A19B; SLC7A3A; SLC1A4

    ATP2C1 has several biochemical functions, for example, ATP binding, calcium ion binding, calcium-transporting ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP2C1 itself. We selected most functions ATP2C1 had, and list some proteins which have the same functions with ATP2C1. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding GUCA1E; EFHA2; CRP; PCDHB1; CCDC167; AASS; ATP2C1; PCDHB11; SPTAN1; PKD2
    calcium-transporting ATPase activity ATP2B1B; ATP2B2; ATP2A1; ATP2B1A; ATP2B3A; ATP2B4; ATP2B1; ATP2B3B; ATP2A1L; ATP2C1
    NOT calcium-transporting ATPase activity ATP2C1
    manganese ion binding FEN1; DCP2; XPNPEP3; NUDT16; PPM1BA; HMGCL; PPM1M; SOD2; PPM1A; ME1
    manganese-transporting ATPase activity ATP2C1; ATP2C2
    metal ion binding SEMG2; CYP2AA2; RNF150A; CYP27C1; GNPTAB; BMPR1A; INSM2; PHF23B; FURIN; ARIH1L
    signal transducer activity OLFR149; BST2; GHRHR2; TAS2R123; OLFR146; OLFR502; PTGER1A; AGTR1B; GPR158; VMN1R50

    ATP2C1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP2C1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP2C1.


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