atp6ap2
Share
  • Official Full Name
  • ATPase, H+ transporting, lysosomal accessory protein 2
  • Background
  • This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases. [provided by RefSeq, Jul 2008]
  • Synonyms
  • ATP6AP2; ATPase, H+ transporting, lysosomal accessory protein 2; M8-9; MRXE; XMRE; XPDS; HT028; MRXSH; ELDF10; ATP6IP2; MSTP009; APT6M8-9; ATP6M8-9; renin receptor; N14F; V-ATPase M8.9 subunit; renin/prorenin receptor; ER-localized type I transmembrane adaptor; embryonic liver differentiation factor 10; ATPase H(+)-transporting lysosomal-interacting protein 2; ATPase, H+ transporting, lysosomal interacting protein 2; vacuolar ATP synthase membrane sector-associated protein M8-9; vacuolar proton ATP synthase membrane sector associated protein M8-9; ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9;
Cat.#:ATP6AP2-2184HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human ATP6AP2 Protein, His-tagged
+Inquiry
Cat.#:ATP6AP2-469HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ATP6AP2 Protein, His-tagged
+Inquiry
Cat.#:Atp6ap2-470RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Atp6ap2 Protein, His-tagged
+Inquiry
Cat.#:ATP6AP2-2443HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ATP6AP2
+Inquiry
Cat.#:ATP6AP2-2444HTag:Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human ATP6AP2, His-tagged
+Inquiry
Cat.#:ATP6AP2-993HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ATP6AP2 protein, GST-tagged
+Inquiry
Cat.#:ATP6AP2-884RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ATP6AP2 Protein
+Inquiry
Cat.#:ATP6AP2-463RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ATP6AP2 Protein, His-tagged
+Inquiry
Cat.#:ATP6AP2-2499CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ATP6AP2
+Inquiry
Cat.#:ATP6AP2-12263ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ATP6AP2
+Inquiry
Cat.#:ATP6AP2-27064THTag:
Source (Host):Species:Human
Product nameNative Human ATP6AP2
+Inquiry
Cat.#:ATP6AP2-8591HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ATP6AP2 293 Cell Lysate
+Inquiry

Involved Pathway

ATP6AP2 involved in several pathways and played different roles in them. We selected most pathways ATP6AP2 participated on our site, such as ACE Inhibitor Pathway, Metabolism of Angiotensinogen to Angiotensins, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP6AP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ACE Inhibitor Pathway
AGTR2; CMA1; ATP6AP2; AGT; ACE; CTSG; AGTR1; CYP11B2
Metabolism of Angiotensinogen to Angiotensins
CPA3; CMA1; CPB1; CPB2; GZMH; ACE; CTSG; ATP6AP2
Metabolism of proteins
ST6GAL2B; TOMM70A; GALNT5; EXOC1; ADAMTSL3; DPH1; CBX8; ADAMTS5; TRAPPC2L; SMC5
Oxidative phosphorylation
ATP6AP1; ATP6V0C; NDUFS6; ATP5E; NDUFB7; NDUFA7; UQCRC2A; NDUFV2; ATP5L; ATP6V0E2
Peptide hormone metabolism
RAB27A; SLC30A6; CPA3; SPCS3; GRP; SLC38A8; PCSK2; MBOAT4; ACE; ATP6AP2
Renin-angiotensin system
LNPEP; CPA3; ANPEP; ENPEP; AGTR1B; ACE; CMA1; KLK1B5; PRCP; MRGPRD
Wnt signaling network
ATP6AP2; RYK; WIF1; IGFBP4; RSPO1; CTHRC1

Protein Function

ATP6AP2 has several biochemical functions, for example, aspartic-type endopeptidase activity, enzyme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP6AP2 itself. We selected most functions ATP6AP2 had, and list some proteins which have the same functions with ATP6AP2. You can find most of the proteins on our site.
Function
Related Protein
Function aspartic-type endopeptidase activity
Related Protein BACE1; ATP6AP2; DDI2; ASPRV1; NRIP2; NAPSA; PGA; ANK2B; CNTNAP5A; NRIP3
Function enzyme binding
Related Protein EIF2AK3; NFKBIA; Ar; ATXN10; EGLN1; NOTCH3; RYR2; CD4; KALRN; LAMP2
Function protein binding
Related Protein MECOM; BOK; CTNNAL1; POU1F1; RRAD; MT3; ADRA2B; PLLP; MGARP; VGLL2
Function receptor activity
Related Protein MED14; P2RY1; PROCR; VMN1R44; TNFRSF25; GFRA1A; XPR1; VMN1R43; CADM1A; GABRA5

Interacting Protein

ATP6AP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP6AP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP6AP2.
USP20; asnB; TMUB1; GOSR1; ESYT2; PDIA3; PON2; WWP2; GOLIM4; LAMTOR5; CHMP2A; ATP6V1G1; SEC22B; FLOT1; ZBTB11; TOP3B; TFRC; ENO1; LGALS1; CLTA