angpt4
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  • Official Full Name
  • angiopoietin 4
  • Background
  • Angiopoietins 3 (Ang-3); is a secretory protein1 and a ligands of Tie-2 receptor tyrosine kinase.2 Ang3 is most abundant in adrenal gland, placenta, thyroid gland, heart and small intestine.1 It inhibits endothelial cell proliferation and survival and blo
  • Synonyms
  • ANGPT4; angiopoietin 4; angiopoietin-4; ANG-3; ANG-4; angiopoietin 3; angiopoietin-3; Ang3; Agpt4; MGC156453
Cat.#:ANGPT4-1587HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Angiopoietin 4
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Cat.#:Angpt4-2519MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Angiopoietin 4
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Cat.#:ANGPT4-207HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ANGPT4 Protein, Fc-tagged
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Cat.#:ANGPT4-208HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ANGPT4 Protein, His-tagged
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Cat.#:ANGPT4-552HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ANGPT4 protein, GST-tagged
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Cat.#:ANGPT4-750HTag:His|GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ANGPT4 protein, His & GST-tagged
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Cat.#:Angpt4-751MTag:His|GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Angpt4 protein, His & GST-tagged
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Cat.#:Angpt4-752RTag:His|T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Angpt4 protein, His & T7-tagged
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Cat.#:ANGPT4-1318HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ANGPT4 cell lysate
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Cat.#:ANGPT4-1614HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ANGPT4 cell lysate
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Involved Pathway

ANGPT4 involved in several pathways and played different roles in them. We selected most pathways ANGPT4 participated on our site, such as Ras signaling pathway, Rap signaling pathway, HIF- signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANGPT4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
FGF13; PLA2G2F; CALM4; RASA4; IKBKG; RAB5B; INSR; RAF1; PTPN11; PIK3R5
Rap signaling pathway
FGFR3; GNAO1; FGF10; TEK; RAC2; FGF5; PARD6A; LPAR2; NRAS; GNAQ
HIF- signaling pathway
RPS6KB2; PIK3R3; PIK3CA; EPO; INSR; TCEB1; TF; LTBR; MKNK1; HIF1A
PIK-Akt signaling pathway
STK11; VEGFB; SOS1; INS2; MAP2K2; LPAR2; NGF; YWHAH; PPP2R2C; IFNA16

Protein Function

ANGPT4 has several biochemical functions, for example, receptor tyrosine kinase binding, transmembrane receptor protein tyrosine kinase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANGPT4 itself. We selected most functions ANGPT4 had, and list some proteins which have the same functions with ANGPT4. You can find most of the proteins on our site.
Function
Related Protein
Function receptor tyrosine kinase binding
Related Protein FLT3LG; TRP53; ZFP259; NCK1; PIK3R2; PTPN2; ARHGEF16; ZNF259; FIZ1; NRG3
Function transmembrane receptor protein tyrosine kinase activator activity
Related Protein GREM1; ANGPT4; EGF; NRG1; EFNA5; NRG3

Interacting Protein

ANGPT4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANGPT4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANGPT4.
daap-5; TEK

ANGPT4 Related Articles

Li, L; Chong, HC; et al. Angiopoietin-like 4 Increases Pulmonary Tissue Leakiness and Damage during Influenza Pneumonia. CELL REPORTS 10:654-663(2015).
Kaneko, K; Tsuji, S; et al. Pathogenesis of childhood idiopathic nephrotic syndrome: a paradigm shift from T-cells to podocytes. WORLD JOURNAL OF PEDIATRICS 11:21-28(2015).