batf3
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  • Official Full Name
  • basic leucine zipper transcription factor, ATF-like 3
  • Background
  • This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.
  • Synonyms
  • BATF3; basic leucine zipper transcription factor, ATF-like 3; basic leucine zipper transcriptional factor ATF-like 3; JDP1; Jun dimerization protein 1; JUNDM1; SNFT; 21 kDa small nuclear factor isolated from T-cells; ATF like 3; B-ATF-3; FLJ36352; FLJ37535; hCG 39202; Jun dimerization protein p21SNFT; 21-kD small nuclear factor isolated from T cells
Cat.#:BATF3-1339RTag:His
Source (Host):YeastSpecies:Rat
Product nameRecombinant Rat BATF3 Protein (1-133 aa), His-tagged
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Cat.#:BATF3-351RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat BATF3 Protein (1-133 aa), His-tagged
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Cat.#:BATF3-2380HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human BATF3 Protein, MYC/DDK-tagged
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Cat.#:BATF3-468HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human basic leucine zipper transcription factor, ATF-like 3, His-tagged
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Cat.#:BATF3-5069HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BATF3, His-tagged
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Cat.#:BATF3-2299MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BATF3 Protein
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Cat.#:BATF3-945RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat BATF3 Protein
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Cat.#:BATF3-4359ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BATF3
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Cat.#:BATF3-1656HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human BATF3 cell lysate
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Involved Pathway

BATF3 involved in several pathways and played different roles in them. We selected most pathways BATF3 participated on our site, such as Calcineurin-regulated NFAT-dependent transcription in lymphocytes, Calcium signaling in the CD4+ TCR pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BATF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
CTLA4; JUNB; DGKA; EGR4; CSF2; POU2F1; BATF3; EGR1; EGR2; IRF4
Calcium signaling in the CD4+ TCR pathway
RCAN1; JUNB; RCAN2; BATF3; CHP; AKAP5; POU2F1; FKBP1A; CSF2

Protein Function

BATF3 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding, transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BATF3 itself. We selected most functions BATF3 had, and list some proteins which have the same functions with BATF3. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein NR2C1; ZKSCAN3; CTCFL; BATF; PYDC3; GMEB2; ZNF148; T; MYF5; SMAD4
Function protein binding
Related Protein LTBP2; GAGE1; ZC3H12A; C9orf86; RPP25L; FBXO32; CHIC2; CLEC18A; RNF34; PRDM10
Function transcription corepressor activity
Related Protein FEV; HDAC3; UBP1; ZFPM2; ATN1; AJUBA; MSC; SAP30; HEYL; SKOR1B
Function transcription factor activity, sequence-specific DNA binding
Related Protein SOX32; IKZF1; SOX7; NFE2L2A; SIX2; ATF6B; DBPA; TBX22; NKX2-8; FOXG1A
Function transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein ZNF148; E2F8; PYDC3; CTCF; GFI1; SP3; RCOR1; ZFPM2; IFI16; YY1

Interacting Protein

BATF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BATF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of BATF3.
DDIT3; APPL1; CREB3; JUN; ATF2; JUNB; JUND; CEBPB; ATF3; DDIT3; CEBPD; CEBPG

BATF3 Related Articles

Schneider, C; Nobs, SP; et al. Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection. PLOS PATHOGENS 10:-(2014).
Alfaro, C; Onate, C; et al. Specialized dendritic cells in cross-presentation of exogenous antigens to cytotoxic T lymphocytes. ANALES DEL SISTEMA SANITARIO DE NAVARRA 36:519-537(2013).