bub1b
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  • Official Full Name
  • budding uninhibited by benzimidazoles 1 homolog beta
  • Background
  • The Mitotic Checkpoint Complex (MCC), which contains Bub1, Bub1b, Bub3, Mad2, and Cdc20, controls chromosome segregation and monitors kinetochore-microtubule interactions (1). During mitosis, the MCC complex inhibits the ubiquitin ligase activity of the A
  • Synonyms
  • BUB1B; budding uninhibited; budding uninhibited by benzimidazoles 1 (yeast homolog), beta; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; Bub1A; BUBR1; MAD3L; SSK1; mitotic checkpoint kinase MAD3L; MAD3/BUB1-related protein kinase; hBUBR1
Cat.#:BUB1B-10335HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BUB1B, GST-tagged
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Cat.#:BUB1B-26124THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human BUB1B
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Cat.#:BUB1B-27105THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human BUB1B
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Cat.#:BUB1B-5973CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken BUB1B
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Cat.#:BUB1B-1371HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human BUB1B (Active), GST-tagged
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Cat.#:BUB1B-8382HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human BUB1B 293 Cell Lysate
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Involved Pathway

BUB1B involved in several pathways and played different roles in them. We selected most pathways BUB1B participated on our site, such as Cell cycle, HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with BUB1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell cycle
FZR1; CSNK2B; MYBL2; ORC1L; GMNN; CENPH; BORA; NCAPH2; MSH4; MIS12
HTLV-I infection
ANAPC1; HLA-DRB5; HLA-DQB1; TGFBR2; DVL3; POLD4; CANX; CD3D; TBPL1; HLA-E

Protein Function

BUB1B has several biochemical functions, for example, ATP binding, protein binding, protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BUB1B itself. We selected most functions BUB1B had, and list some proteins which have the same functions with BUB1B. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein MYH11; TGFBR1; IP6K1; HSP90B1; ITM2C; P2RY4; BAT1; MYO6A; UCKL1A; TAP2
Function protein binding
Related Protein NUDT21; ARFGAP3; ZNF167; SETD8; RAB35; GRASP; GJB6; RGS16; NFYA; HMBOX1
Function protein kinase activity
Related Protein SRC; INSRA; PLK1; STK24; ERBB3B; MAP3K11; EPHA4; CCL5; ADRBK2; ARAF
Function protein serine/threonine kinase activity
Related Protein CDK11B; PIK3R4; LMTK2; IRAK1; NEK6; PRKCHB; DCLK1; MYLK4; PLK4; ROCK1

Interacting Protein

BUB1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BUB1B here. Most of them are supplied by our site. Hope this information will be useful for your research of BUB1B.
CDC20; BUB3