|Official Full Name||calsequestrin 2 (cardiac muscle)|
|Background||The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin;is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding;protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular;tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease;characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.|
|Synonyms||CASQ2; calsequestrin 2 (cardiac muscle); calsequestrin-2; PDIB2; calsequestrin, cardiac muscle isoform; calsequestrin 2, fast-twitch, cardiac muscle; FLJ26321; FLJ93514|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CASQ2 involved in several pathways and played different roles in them. We selected most pathways CASQ2 participated on our site, such as Calcium Regulation in the Cardiac Cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CASQ2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Calcium Regulation in the Cardiac Cell||GJB1; GJB6; RGS14A; RGS7; GJB3; GJA8; PKIB; CHRM2; CX35.4; GNB3B|
CASQ2 has several biochemical functions, for example, calcium ion binding, calcium-dependent protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CASQ2 itself. We selected most functions CASQ2 had, and list some proteins which have the same functions with CASQ2. You can find most of the proteins on our site.
|calcium ion binding||ITIH1; PCDHA4; SWAP70B; VCANB; C1RA; DLA; MYL12B; PCDHGA8; ELTD1; MMP1A|
|calcium-dependent protein binding||MBL1; CCDC167; NELF; VPS37C; PDCD6; MYO5A; MASP2; SYT8; VPS37B; DMBT1|
|protein binding||MYBPC1; CCDC106; SUB1; WEE1; DYRK1A; NECAB2; CDC27; CRTC2; CAV1; PPIL2|
|protein homodimerization activity||FAM109B; BCL2A1; MTUS2; NR0B1; TAP1; HNF1B; MVD; ECE1; SMAD4; UGT1A6|
|protein kinase C binding||PRKCSH; HINT1; GLRX3; PRKCB; AVPR1A; HDAC7A; GNB2L1; AVPR1B; TOP2A; PICK1|
CASQ2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CASQ2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CASQ2.