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Official Full Name calsequestrin 2 (cardiac muscle)
Background The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin;is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding;protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular;tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease;characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
Synonyms CASQ2; calsequestrin 2 (cardiac muscle); calsequestrin-2; PDIB2; calsequestrin, cardiac muscle isoform; calsequestrin 2, fast-twitch, cardiac muscle; FLJ26321; FLJ93514
    • Species :
    • Canine
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • Dog Heart
    • E.coli
    • HEK293
    • Human
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CASQ2-0436H Recombinant Human CASQ2 Protein, GST-Tagged Wheat Germ GST
    Human CASQ2-4248H Recombinant Human Calsequestrin 2 (Cardiac Muscle), His-tagged Human His
    Human CASQ2-7826HCL Recombinant Human CASQ2 293 Cell Lysate HEK293 N/A
    Mouse Casq2-1745M Recombinant Mouse Casq2 protein, His & T7-tagged E.coli His/T7
    Mouse CASQ2-2760M Recombinant Mouse CASQ2 Protein Mammalian Cell His
    Canine CASQ2-30C Native Canine CASQ2 Dog Heart N/A
    Chicken CASQ2-6095C Recombinant Chicken CASQ2 Mammalian Cell His
    Zebrafish CASQ2-789Z Recombinant Zebrafish CASQ2 Mammalian Cell His

    CASQ2 involved in several pathways and played different roles in them. We selected most pathways CASQ2 participated on our site, such as Calcium Regulation in the Cardiac Cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CASQ2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium Regulation in the Cardiac Cell GJB1; GJB6; RGS14A; RGS7; GJB3; GJA8; PKIB; CHRM2; CX35.4; GNB3B

    CASQ2 has several biochemical functions, for example, calcium ion binding, calcium-dependent protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CASQ2 itself. We selected most functions CASQ2 had, and list some proteins which have the same functions with CASQ2. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding ITIH1; PCDHA4; SWAP70B; VCANB; C1RA; DLA; MYL12B; PCDHGA8; ELTD1; MMP1A
    calcium-dependent protein binding MBL1; CCDC167; NELF; VPS37C; PDCD6; MYO5A; MASP2; SYT8; VPS37B; DMBT1
    protein binding MYBPC1; CCDC106; SUB1; WEE1; DYRK1A; NECAB2; CDC27; CRTC2; CAV1; PPIL2
    protein homodimerization activity FAM109B; BCL2A1; MTUS2; NR0B1; TAP1; HNF1B; MVD; ECE1; SMAD4; UGT1A6
    protein kinase C binding PRKCSH; HINT1; GLRX3; PRKCB; AVPR1A; HDAC7A; GNB2L1; AVPR1B; TOP2A; PICK1

    CASQ2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CASQ2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CASQ2.

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