Recombinant Human CASQ2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CASQ2-6334H
• Product Overview: CASQ2 MS Standard C13 and N15-labeled recombinant protein (NP_001223) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 46.4 kDa
• AA Sequence: MKRTHLFIVGIYFLSSCRAEEGLNF PTYDGKDRVVSLSEKNFKQVLKKYD LLCLYYHEPVSSDKVTQKQFQLKEI VLELVAQVLEHKAIGFVMVDAKKEA KLAKKLGFDEEGSLYILKGDRTIEF DGEFAADVLVEFLLDLIEDPVEIIS SKLEVQAFERIEDYIKLIGFFKSED SEYYKAFEEAAEHFQPYIKFFATFD KGVAKKLSLKMNEVDFYEPFMDEPI AIPNKPYTEEELVEFVKEHQRPTLR RLRPEEMFETWEDDLNGIHIVAFAE KSDPDGYEFLEILKQVARDNTDNPD LSILWIDPDDFPLLVAYWEKTFKID LFRPQIGVVNVTDADSVWMEIPDDD DLPTAEELEDWIEDVLSGKINTEDD DEDDDDDDNSDEEDNDDSDDDDDET RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CASQ2 calsequestrin 2 [ Homo sapiens (human) ]
• Official Symbol: CASQ2
• Synonyms: CASQ2; calsequestrin 2 (cardiac muscle); calsequestrin-2; PDIB2; calsequestrin, cardiac muscle isoform; calsequestrin 2, fast-twitch, cardiac muscle; FLJ26321; FLJ93514
• Gene ID: 845
• mRNA Refseq: NM_001232
• Protein Refseq: NP_001223
• MIM: 114251
• UniProt ID: O14958