Recombinant Human CASQ2 Protein, GST-Tagged

• Cat.No.: CASQ2-0436H
• Product Overview: Human CASQ2 full-length ORF (AAH22288, 20 a.a. - 399 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 67.54 kDa
• AA Sequence: EEGLNFPTYDGKDRVVSLSEKNFKQ VLKKYDLLCLYYHEPVSSDKVTQKQ FQLKEIVLELVAQVLEHKAIGFVMV DAKKEAKLAKKLGFDEEGSLYILKG DRTIEFDGEFAADVLVEFLLDLIED PVEIISSKLEVQAFERIEDYIKLIG FFKSEDSEYYKAFEEAAEHFQPYIK FFATFDKGVAKKLSLKMNEVDFYEP FMDEPIAIPNKPYTEEELVEFVKEH QRPTLRRLRPEEMFETWEDDLNGIH IVAFAEKSDPDGYEFLEILKQVARD NTDNPDLSILWIDPDDFPLLVAYWE KTFKIDLFRPQIGVVNVTDADSVWM EIPDDDDLPTAEELEDWIEDVLSGK INTEDDDEDDDDDDNSDEEDNDDSD DDDDE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CASQ2 calsequestrin 2 (cardiac muscle) [ Homo sapiens ]
• Official Symbol: CASQ2
• Synonyms: CASQ2; calsequestrin 2 (cardiac muscle); calsequestrin-2; PDIB2; calsequestrin, cardiac muscle isoform; calsequestrin 2, fast-twitch, cardiac muscle; FLJ26321; FLJ93514
• Gene ID: 845
• mRNA Refseq: NM_001232
• Protein Refseq: NP_001223
• MIM: 114251
• UniProt ID: O14958