Recombinant Human CASQ2 Protein, GST-Tagged

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Recombinant Human CASQ2 Protein, GST-Tagged

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Cat.No. : CASQ2-0436H
Product Overview : Human CASQ2 full-length ORF (AAH22288, 20 a.a. - 399 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 67.54 kDa
AA Sequence : EEGLNFPTYDGKDRV VSLSEKNFKQVLKKY DLLCLYYHEPVSSDK VTQKQFQLKEIVLEL VAQVLEHKAIGFVMV DAKKEAKLAKKLGFD EEGSLYILKGDRTIE FDGEFAADVLVEFLL DLIEDPVEIISSKLE VQAFERIEDYIKLIG FFKSEDSEYYKAFEE AAEHFQPYIKFFATF DKGVAKKLSLKMNEV DFYEPFMDEPIAIPN KPYTEEELVEFVKEH QRPTLRRLRPEEMFE TWEDDLNGIHIVAFA EKSDPDGYEFLEILK QVARDNTDNPDLSIL WIDPDDFPLLVAYWE KTFKIDLFRPQIGVV NVTDADSVWMEIPDD DDLPTAEELEDWIED VLSGKINTEDDDEDD DDDDNSDEEDNDDSD DDDDE
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CASQ2 calsequestrin 2 (cardiac muscle) [ Homo sapiens ]
Official Symbol : CASQ2
Synonyms : CASQ2; calsequestrin 2 (cardiac muscle); calsequestrin-2; PDIB2; calsequestrin, cardiac muscle isoform; calsequestrin 2, fast-twitch, cardiac muscle; FLJ26321; FLJ93514;
Gene ID : 845
mRNA Refseq : NM_001232
Protein Refseq : NP_001223
MIM : 114251
UniProt ID : O14958

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