CD151 Protein, CD151 molecule (Raph blood group)


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Official Full Name CD151 molecule (Raph blood group)
Background CD151 is a tetraspanin and is thought to aid in the creation of multi-protein complexes at the surface of cells. CD151 forms secure laminin-binding compounds in the kidney, using integrins alpha3beta1 and alpha6beta1, and in the skin, using alpha3beta1 and alpha6beta4. CD151 may also play an important role in the inner ear and may also be involved in erythropoiesis. CD151 may be an important marker for prostate cancer and the higher the level of CD151, the less likely the patient survives. Research has shown that mice lacking CD151 have a damaged re-epithelialization process and lack wound healing ability.
Synonyms CD151; CD151 molecule (Raph blood group); CD151 antigen , CD151 antigen (Raph blood group); CD151 antigen; PETA 3; RAPH; SFA 1; TSPAN24; tspan-24; tetraspanin-24; membrane glycoprotein SFA-1; CD151 antigen (Raph blood group); hemidesmosomal tetraspanin CD151; platelet surface glycoprotein gp27; platelet-endothelial tetraspan antigen 3; platelet-endothelial cell tetraspan antigen 3; GP27; MER2; SFA1; PETA-3
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Rhesus monkey
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • hIgG1
    • hIgG4
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD151-0722H Recombinant Human CD151 Protein Wheat Germ N/A
    Human CD151-0723H Recombinant Human CD151 Protein, GST-Tagged Wheat Germ GST
    Human CD151-7684HCL Recombinant Human CD151 293 Cell Lysate HEK293 N/A
    Mouse CD151-3035M Recombinant Mouse CD151 Protein Mammalian Cell His
    Rat CD151-1236R Recombinant Rat CD151 Protein Mammalian Cell His
    Rhesus monkey CD151-1585R Recombinant Rhesus Monkey CD151 Protein HEK293 N/A
    Rhesus monkey CD151-1586R Recombinant Rhesus Monkey CD151 Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey CD151-1587R Recombinant Rhesus Monkey CD151 Protein, hIgG4-tagged HEK293 hIgG4
    Rhesus Macaque CD151-718R Recombinant Rhesus monkey CD151 Protein, His-tagged Mammalian Cell His
    Chicken CD151-1611C Recombinant Chicken CD151 Mammalian Cell His
    Zebrafish CD151-1555Z Recombinant Zebrafish CD151 Mammalian Cell His

    CD151 involved in several pathways and played different roles in them. We selected most pathways CD151 participated on our site, such as Alpha6-Beta4 Integrin Signaling Pathway, Assembly of collagen fibrils and other multimeric structures, Cell junction organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD151 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Alpha6-Beta4 Integrin Signaling Pathway EIF4EBP1; DST; DSP; CDKN1A; EGFR; COL17A1; EIF4E; CD151L; EIF4EB; CD151
    Assembly of collagen fibrils and other multimeric structures TLL2; LOXL1; CTSL2; COL2A1; CTSS; MMP13; COL1A1; COL10A1A; MMP20; COL6A3
    Cell junction organization CDH4; CDH12; PLEC; DST; CDH8; CLDN16; CDH6; PLECA; CDH13; FERMT2
    Cell-Cell communication CADM2; PLEC; KIRRELB; CDH13; KIRRELA; CDH17; DCC; ANG; CADM2A; SKAP2
    Collagen formation COL8A1A; TLDC2; PCOLCE2; COL5A2; COL28A1; LOXL3; MMP20; COL23A1; COL25A1; TLL2
    Extracellular matrix organization EFEMP2; MMP24; FAM49BA; MGC174152; ADAMTS4; MFAP4; LOC100686744; LTBP4; HAPLN1; FMOD
    Type I hemidesmosome assembly PLECA; DST; COL17A1A; CD151

    CD151 has several biochemical functions, for example, integrin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD151 itself. We selected most functions CD151 had, and list some proteins which have the same functions with CD151. You can find most of the proteins on our site.

    Function Related Protein
    integrin binding ANXA7; ILK; ADAM15; CD151; COL4A3; CYR61; TLN1; WISP1B; ITGB1BP2; ADAMTS8
    protein binding PCGF2; NAGK; MEIS1B; NUDT18; MYO5B; SENP1; CSDC2; RAD23A; PAIP2; WDR74

    CD151 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD151 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD151.


    Tang, QH; Liu, ZY; et al. Involvement of activation of C-met signaling pathway in CD151-induced HUVECs angiogenesis. JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES 35:35-41(2015).
    Matsumoto, N; Morine, Y; et al. Role of CD151 expression in gallbladder carcinoma. SURGERY 156:1212-1217(2014).

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