cdc16
Share
  • Official Full Name
  • cell division cycle 16 homolog (S. cerevisiae)
  • Background
  • This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein interaction. Multiple alternatively spliced variants, encoding the same protein, have been identified.
  • Synonyms
  • CDC16; cell division cycle 16 homolog (S. cerevisiae); CDC16 (cell division cycle 16, S. cerevisiae, homolog) , CDC16 cell division cycle 16 homolog (S. cerevisiae); cell division cycle protein 16 homolog; ANAPC6; anaphase promoting complex; subunit 6; APC6; CUT9; Anaphase promoting complex subunit 6; Anaphase-promoting complex subunit 6; Apc 6; CDC 16; CDC16 (cell division cycle 16 S. cerevisiae homolog); CDC16 homolog; CDC16 protein; CDC16_HUMAN; CDC16Hs; Cell division cycle 16 homolog; Cyclosome subunit 6; anaphase-promoting complex, subunit 6
Cat.#:CDC16-0902HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDC16 Protein, GST-Tagged
+Inquiry
Cat.#:CDC16-1270HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDC16 protein, His & T7-tagged
+Inquiry
Cat.#:CDC16-757RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CDC16 Protein, His-tagged
+Inquiry
Cat.#:CDC16-1412CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CDC16
+Inquiry
Cat.#:CDC16-3514ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CDC16
+Inquiry
Cat.#:CDC16-7669HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CDC16 293 Cell Lysate
+Inquiry
Cat.#:CDC16-7670HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CDC16 293 Cell Lysate
+Inquiry

Involved Pathway

CDC16 involved in several pathways and played different roles in them. We selected most pathways CDC16 participated on our site, such as Cell cycle, Oocyte meiosis, Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell cycle
SFN; E2F2; YWHAH; E2F4; TGFB2; GINS4; CENPQ; UBE2V2; PLK1; CDK1
Oocyte meiosis
PTTG2; REC8B; CCNB1; CAMK2D2; ADCY2B; SLK; CTH1; SMC3; RPS6KA3A; PRKACAA
Ubiquitin mediated proteolysis
UBE2D1B; UBE2A; UBA6; PIAS4; PIAS4A; MID1; MGRN1; FBXW7; UBE2U; MGRN1A
Progesterone-mediated oocyte maturation
SPDYB; PIK3R3A; Adcy4; MAD2L2; CDC25A; CDC25C; PRKACAA; AKT2L; PIK3R1; GNAI1
HTLV-I infection
POLE4; ZFP36; HLA-DRB5; HLA-DMA; WNT5B; LCK; H2-AB1; CCND1; IL2RG; ICAM1

Protein Function

CDC16 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC16 itself. We selected most functions CDC16 had, and list some proteins which have the same functions with CDC16. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein DCDC2B; CALCRL; CHMP4A; MTMR9; RAB37; C1orf94; RPS7; RPS3; FAM114A1; OPRK1

Interacting Protein

CDC16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC16 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC16.
CDC26; CDC27; CDC20; ANAPC1

CDC16 Related Articles

Imai, A; Yoshie, S; et al. EPI64 Protein Functions as a Physiological GTPase-activating Protein for Rab27 Protein and Regulates Amylase Release in Rat Parotid Acinar Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 286:33854-33862(2011).
Luo, Y; Sarabi, SA; et al. Expression pattern of NuIP gene in adult mouse brain. BRAIN RESEARCH 1302:42-53(2009).