CDC37 Protein, cell division cycle 37 homolog

CDC37

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CDC37

Official Full Name cell division cycle 37 homolog
Background CDC37 is an important component of the HSP90 chaperone complex. It was initially identified for its involvement in cell-cycle progression and was later found to have a much broader role as a chaperone for a wide variety of kinases and other proteins. CDC3
Synonyms CDC37; cell division cycle 37 homolog (S. cerevisiae); CDC37 (cell division cycle 37, S. cerevisiae, homolog) , CDC37 cell division cycle 37 homolog (S. cerevisiae); hsp90 co-chaperone Cdc37; CDC37 (cell division cycle 37; S. cerevisiae; homolog)
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Cdc37-855M Recombinant Mouse Cdc37 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human CDC37-0930H Recombinant Human CDC37 Protein, GST-Tagged Wheat Germ GST
    Human CDC37-11006H Recombinant Human CDC37, GST-tagged E.coli GST
    Human CDC37-124H Recombinant Human CDC37 protein, T7/His-tagged E.coli T7/His
    Human CDC37-26222TH Recombinant Human CDC37, His-tagged E.coli His
    Human CDC37-3072H Recombinant Human CDC37, GST tagged Insect Cell GST
    Human CDC37-3124H Recombinant Human CDC37 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CDC37-331H Recombinant Human Cell Division Cycle 37 Homolog (S. cerevisiae) E.coli N/A
    Human CDC37-648HCL Recombinant Human CDC37 cell lysate Insect Cell N/A
    Human CDC37-798H Recombinant Human, CDC37 His-tagged E.coli His
    Mouse CDC37-001MCL Recombinant Mouse CDC37 cell lysate Insect Cell N/A
    Mouse CDC37-403M Recombinant Mouse Cdc37, Gly & Pro tagged Insect Cell His
    Mouse CDC37-417M Recombinant Mouse Cdc37, His-GST tagged Insect Cell Fc
    Rat CDC37-1275R Recombinant Rat CDC37 Protein Mammalian Cell His
    Chicken CDC37-6260C Recombinant Chicken CDC37 Mammalian Cell His
    Zebrafish CDC37-11269Z Recombinant Zebrafish CDC37 Mammalian Cell His

    CDC37 involved in several pathways and played different roles in them. We selected most pathways CDC37 participated on our site, such as AhR pathway, Constitutive Signaling by EGFRvIII, Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC37 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    AhR pathway NQO1; AHR; FLG; JUND; CDC37; CDKN1A; AHRR; CYP1A2; CYP1B1; EGFR
    Constitutive Signaling by EGFRvIII CDC37
    Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants CDC37
    Disease CCDC167; NMT2; GPC6; VPS37A; AP1G1; ARF1; KERA; TICAM1; RNF43; AP1B1
    Diseases of signal transduction MIB1; RBP1; FGFR1OP2; KREMEN2; OPN1SW; HDAC5; TRIM24; RNF43; TNKS; FKBP1A
    LKB1 signaling events SIK3; MARK4; MARK2; MAP2; STK11IP; CTSD; CDC37
    PI3K-Akt signaling pathway CHAD; EFNA4; EFNA2; EFNA3; CSH1; COMP; LAMC3; PRP2; CSH; CSF3R
    Signal Transduction TLE3B; PDK3; ARHGAP44; PROKR1; CIT; PYYA; OR7D2; NOTUM1A; OXGR1; LGR5

    CDC37 has several biochemical functions, for example, Hsp90 protein binding, chaperone binding, heat shock protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC37 itself. We selected most functions CDC37 had, and list some proteins which have the same functions with CDC37. You can find most of the proteins on our site.

    Function Related Protein
    Hsp90 protein binding EIF2AK3; UNC45B; STUB1; CSNK2A1; ARNTL; RPS3; ERBB2; USP19; AHR; CDC37
    chaperone binding AHSA2; STIP1; DNAJA4; DNAJA3B; AHSA1L; SYVN1; BIRC5; DNAJB6; TSACC; DNAJA2
    heat shock protein binding LMAN2; DNAJA2; KCNJ11; DNAJA2L; CDC37L1; PACRG; DNAJA4; DAXX; FKBP4; DNAJC7
    kinase binding CDC37; SLC2A1; TRIP6; LDHA; TOLLIP; PER1; STUB1; CEBPB; CDC6; WWC2
    mitogen-activated protein kinase kinase kinase binding MAP2K1; MAP3K11; CDC37; CDC42; MAPK1; PPEF2; MAPK8IP3; TRAF6; TCF3; STK38
    protein C-terminus binding SDCBP2; SNF8; RBFOX1; BCL10; XRCC4; PPP1R9B; BLOC1S2; ITPR1; PLEKHB1; EFHC1
    protein binding ASPSCR1; CCS; BCCIP; RTN4R; NOTCH4; TOMM20; HYLS1; IFT43; VGLL4; MSH5
    protein kinase B binding CDC37; PDE3B; PINK1; BAD; RARA; TRAF6; BCL10; ANKRD2; CCDC88A; APPL1
    protein kinase regulator activity APC; FAF1; KIDINS220; CDK5RAP1; ANKRD54; CDC37; RAC2; KIDINS220B; CSNK2B
    unfolded protein binding SCG5; PFDN2; HSP90B1; SYVN1; CANX; DNAJB1; DNAJB5; HSPA2; HSP26; AIP

    CDC37 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC37 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC37.

    HSP90AA1; LRRK2

    Cao, FF; Xu, LM; et al. IP-FCM Platform Detects the Existence and Regulator-Caused Dissociation of Components in Naturally Assembled HSP90 Complex. CYTOMETRY PART A 85:359-367(2014).
    Du, C; Wingard, JR; et al. Serum IgG Responses against Aspergillus Proteins before Hematopoietic Stem Cell Transplantation or Chemotherapy Identify Patients Who Develop Invasive Aspergillosis. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 18:1927-1934(2012).

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