CDC42BPB
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Official Full Name
CDC42 binding protein kinase beta (DMPK-like) -
Overview
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. -
Synonyms
CDC42BPB;CDC42 binding protein kinase beta (DMPK-like);CDC42 binding protein kinase beta (DMPK like);serine/threonine-protein kinase MRCK beta;KIAA1124;MRCKB;MRCK beta;CDC42BP-beta;DMPK-like beta;myotonic dystrophy protein kinase-like beta;CDC42
Recombinant Proteins
- Human
- Rat
- Mouse
- Zebrafish
- Insect Cells
- Wheat Germ
- Mammalian Cells
- Sf9 Cells
- HEK293
- GST
- His
- Non
- Avi
- Fc
Involved Pathway
CDC42BPB involved in several pathways and played different roles in them. We selected most pathways CDC42BPB participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC42BPB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDC42BPB has several biochemical functions, for example, ATP binding,Rho GTPase binding,magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC42BPB itself. We selected most functions CDC42BPB had, and list some proteins which have the same functions with CDC42BPB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein serine/threonine kinase activity | MAP3K2,MAPK13,SRPK1B,SGK2A,DYRK1A,MELK,TSSK2,SRPK1A,SRPK1,FASTK |
| protein kinase activity | RBM4.3,CDKL3,FGFR1B,SLKA,VRK1,ERBB4A,PDPK1B,PRKG2,TRIOA,SBK3 |
| magnesium ion binding | IRAK4,PTEN,STK38L,MARK2,GTPBP10,PPA2,GCLC,MAP3K6,ILVBL,TDP2B |
| Rho GTPase binding | CSDA,ARHGEF2,ROCK2,DAAM1,KIF3B,ROCK2A,DAAM1B,AKAP13,DOCK11,DOCK9 |
| ATP binding | BRAF,SLFNL1,MAP2K6,NMNAT2,CDK17,P2RX1,SHPRH,KIF1B,ORC1L,POMK |
Interacting Protein
CDC42BPB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC42BPB here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC42BPB.
MYO18A;TJP1;RPL3;RPL35;DCD;KRT78;BRIX1;DDX21;PYGM;CDC42;MAP2K5;RIPK1;CDC42BPA;opuD;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;pi3p
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References
- Li, L; Wan, J; et al. Protein kinases paralleling late-phase LTP formation in dorsal hippocampus in the rat. NEUROCHEMISTRY INTERNATIONAL 76:50-58(2014).
