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CDH23

Official Full Name

cadherin-related 23
Overview

This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
Synonyms

CDH23; cadherin-related 23; cadherin related 23 , cadherin like 23 , DFNB12, USH1D; cadherin-23; cadherin related family member 23; CDHR23; Age related hearing loss 1; Ahl 1; Ahl; Ahl1; Bob; Bobby; Bus; Bustling; Cadherin 23; Cadherin23; CDH 23; Mdfw; Modifier of deaf waddler; nmf112; nmf181; nmf252; Otocadherin; USH 1D; USH1 D; USH1D; Waltzer; cadherin-like 23; OTTHUMP00000020837; OTTHUMP00000020838; cadherin-related family member 23;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

C
Myc
DDK
GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CDH23-11038H	Recombinant Human CDH23, GST-tagged	E.coli	GST	1-352a.a.	$319 / 25ug
Human	CDH23-0986H	Recombinant Human CDH23 Protein	Wheat Germ	N/A		Inquiry
Human	CDH23-0987H	Recombinant Human CDH23 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CDH23-471H	Recombinant Human CDH23 Protein, His-tagged	E.coli	His	His34~Phe236	$298 / 10ug
Human	CDH23-429H	Recombinant Human CDH23 Protein, MYC/DDK-tagged, C13 and N15-labeled	HEK293	C-Myc/DDK		Inquiry
Human	CDH23-3148HF	Recombinant Full Length Human CDH23 Protein	In Vitro Cell Free System		531 amino acids	Inquiry
Rat	CDH23-1293R	Recombinant Rat CDH23 Protein	Mammalian Cell	His		Inquiry
Rat	CDH23-951R	Recombinant Rat CDH23 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	CDH23-951R-B	Recombinant Rat CDH23 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	CDH23-12819Z	Recombinant Zebrafish CDH23	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
CDH23 Related Articles

CDH23 involved in several pathways and played different roles in them. We selected most pathways CDH23 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CDH23 has several biochemical functions, for example, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH23 itself. We selected most functions CDH23 had, and list some proteins which have the same functions with CDH23. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	CHP2;VCAN;RCV1;NID1;GRIN1;DNER;CAPN2A;EHD1B;CPNE6
protein binding	RGR;RHO;TRIM41;AKR7A3;MAGEB2;SARM1;ETS1;RNF2;DGAT1

CDH23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH23 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH23.

Dlg4

Tang, PC; Watson, GM; et al. Cadherin-23 May Be Dynamic in Hair Bundles of the Model Sea Anemone Nematostella vectensis. PLOS ONE 9:-(2014).

Lagziel, A; Overlack, N; et al. Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D. MOLECULAR VISION 15:1843-1857(2009).