cdh23
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  • Official Full Name
  • cadherin-related 23
  • Background
  • This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
  • Synonyms
  • CDH23; cadherin-related 23; cadherin related 23 , cadherin like 23 , DFNB12, USH1D; cadherin-23; cadherin related family member 23; CDHR23; Age related hearing loss 1; Ahl 1; Ahl; Ahl1; Bob; Bobby; Bus; Bustling; Cadherin 23; Cadherin23; CDH 23; Mdfw; Modifier of deaf waddler; nmf112; nmf181; nmf252; Otocadherin; USH 1D; USH1 D; USH1D; Waltzer; cadherin-like 23; OTTHUMP00000020837; OTTHUMP00000020838; cadherin-related family member 23
Cat.#:CDH23-0986HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDH23 Protein
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Cat.#:CDH23-0987HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDH23 Protein, GST-Tagged
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Cat.#:CDH23-471HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDH23 Protein, His-tagged
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Cat.#:CDH23-11038HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDH23, GST-tagged
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Cat.#:CDH23-1293RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CDH23 Protein
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Cat.#:CDH23-12819ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CDH23
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Protein Function

CDH23 has several biochemical functions, for example, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH23 itself. We selected most functions CDH23 had, and list some proteins which have the same functions with CDH23. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein PCDH1GC6; ANXA1; MMP3; MMP20; PVALB8; TESCB; ANXA2B; PCDH18B; KCNIP2; PCDHGA2
Function protein binding
Related Protein TP63; AMIGO2; ZNF433; MAGEB18; COL18A1; MIB1; HRK; STXBP1; ITGB1BP3; TNNI3

Interacting Protein

CDH23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH23 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH23.
Dlg4

CDH23 Related Articles

Tang, PC; Watson, GM; et al. Cadherin-23 May Be Dynamic in Hair Bundles of the Model Sea Anemone Nematostella vectensis. PLOS ONE 9:-(2014).
Lagziel, A; Overlack, N; et al. Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D. MOLECULAR VISION 15:1843-1857(2009).