cdh8
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  • Official Full Name
  • cadherin 8, type 2
  • Background
  • This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the proteins homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
  • Synonyms
  • CDH8; cadherin 8, type 2; cadherin-8; Nbla04261
Cat.#:CDH8-0995HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDH8 Protein, GST-Tagged
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Cat.#:CDH8-3148HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CDH8 Protein, MYC/DDK-tagged
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Cat.#:CDH8-160HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human CDH8, Fc Chimera
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Cat.#:CDH8-26742THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CDH8
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Cat.#:CDH8-602HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CDH8, His tagged
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Cat.#:CDH8-625HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human CDH8
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Cat.#:Cdh8-24RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Cdh8, LEVLFQ tagged
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Cat.#:Cdh8-8760RTag:FC/His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Cdh8, His tagged
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Cat.#:CDH8-777RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CDH8 Protein, His-tagged
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Cat.#:CDH8-3730CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CDH8
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Cat.#:CDH8-2738HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CDH8 cell lysate
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Cat.#:CDH8-991RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CDH8 cell lysate
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Involved Pathway

CDH8 involved in several pathways and played different roles in them. We selected most pathways CDH8 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adherens junctions interactions
CTNNB2; CDH6; PTBP3; CDH12A; CDH18A; CDH18; CTNNB1; CADM2; CDH3; CTNND1
Cell junction organization
PLEC; CTNND1; CDH24; CDH10A; PVRL2L; CDH7; CDH10; F11R.2; CADM2A; CDH12
Cell-Cell communication
CDH4; CD151; CTNND1; SKAP2; CDH3; ITGB1B.1; FBLIM1; DSCAM; DCC; COL17A1A
Cell-cell junction organization
CDH4; CDH9; CDH12A; CLDN20; CDH6; CDH24; CLDN16; CLDN23; CDH10A; CDH17

Protein Function

CDH8 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH8 itself. We selected most functions CDH8 had, and list some proteins which have the same functions with CDH8. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein DNASE1L3; CAPN1; TLL2; BMP1; RHBDL3; REPS1; CALM3A; RAB11FIP4; CBLB; CD97