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CDKN3

  • Official Full Name

    cyclin-dependent kinase inhibitor 3

  • Overview

    The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    CDKN3; cyclin-dependent kinase inhibitor 3; CDI1; CDK2 associated dual specificity phosphatase; cyclin dependent kinase inhibitor; KAP; kinase associated phosphatase; kinase-associated phosphatase; Cdk-associated protein phosphatase; cyclin-dependent kina;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CDKN3-26472TH Recombinant Human CDKN3 N/A
Human CDKN3-700H Recombinant Human Cyclin-Dependent Kinase Inhibitor 3, GST-tagged E.coli GST
Human CDKN3-26470TH Recombinant Human CDKN3, His-tagged E.coli His 212 amino acids
Human CDKN3-942H Recombinant Human Cyclin-Dependent Kinase Inhibitor 3, His-tagged E.coli His
Human CDKN3-6980H Recombinant Human CDKN3, GST-tagged Sf9 Insect Cell GST Full length
Human CDKN3-1067H Recombinant Human CDKN3 Protein, GST-Tagged Wheat Germ GST
Human CDKN3-7609HCL Recombinant Human CDKN3 293 Cell Lysate HEK293 N/A
Human CDKN3-599H Recombinant Human CDKN3 Protein, His/GST-tagged E.coli His/GST Met1~Arg212
Human CDKN3-3235HF Recombinant Full Length Human CDKN3 Protein, GST-tagged In Vitro Cell Free System GST 172 amino acids
Human CDKN3-2236H Recombinant Human CDKN3 Protein (1-212 aa), His-tagged Yeast His 1-212 aa
Mouse CDKN3-3229M Recombinant Mouse CDKN3 Protein Mammalian Cell His
Mouse CDKN3-1541M Recombinant Mouse CDKN3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CDKN3-1541M-B Recombinant Mouse CDKN3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CDKN3-798R Recombinant Rhesus monkey CDKN3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CDKN3-624R Recombinant Rhesus Macaque CDKN3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CDKN3-624R-B Recombinant Rhesus Macaque CDKN3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CDKN3-7370Z Recombinant Zebrafish CDKN3 Mammalian Cell His
Chicken CDKN3-4556C Recombinant Chicken CDKN3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CDKN3 involved in several pathways and played different roles in them. We selected most pathways CDKN3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDKN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

CDKN3 has several biochemical functions, for example, protein binding, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDKN3 itself. We selected most functions CDKN3 had, and list some proteins which have the same functions with CDKN3. You can find most of the proteins on our site.

Function Related Protein
protein bindingFDXR;ENTPD5;HDAC2;CCDC6;KTI12;ISYNA1;OGT;SH3BP2;CENPK
protein serine/threonine phosphatase activityPTEN;PPM1L;CTDNEP1;PDP1;TIMM50;PPM1LB;PPM1BB;PPM1LA;PPP1R15B
protein tyrosine phosphatase activityDUSP11;TPTE;PTPN22;PTPN3;MTM1;PTPRNA;PTPRJ;SSH3;DUSP16
protein tyrosine/serine/threonine phosphatase activityPTP4A3;PTPRQ;DUSP16;CDKN3;CDC14A;PTEN;DUSP14;DUSP4;DUSP10

CDKN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDKN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDKN3.

CDK2; CDC28; CDK1; CDK3

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