cdkn3
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  • Official Full Name
  • cyclin-dependent kinase inhibitor 3
  • Background
  • The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • CDKN3; cyclin-dependent kinase inhibitor 3; CDI1; CDK2 associated dual specificity phosphatase; cyclin dependent kinase inhibitor; KAP; kinase associated phosphatase; kinase-associated phosphatase; Cdk-associated protein phosphatase; cyclin-dependent kina
Cat.#:CDKN3-2236HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human CDKN3 Protein (1-212 aa), His-tagged
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Cat.#:CDKN3-1067HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDKN3 Protein, GST-Tagged
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Cat.#:CDKN3-599HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDKN3 Protein, His/GST-tagged
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Cat.#:CDKN3-26470THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDKN3, His-tagged
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Cat.#:CDKN3-26472THTag:
Source (Host):Species:Human
Product nameRecombinant Human CDKN3
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Cat.#:CDKN3-6980HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human CDKN3, GST-tagged
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Cat.#:CDKN3-700HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Cyclin-Dependent Kinase Inhibitor 3, GST-tagged
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Cat.#:CDKN3-942HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Cyclin-Dependent Kinase Inhibitor 3, His-tagged
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Cat.#:CDKN3-3229MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CDKN3 Protein
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Cat.#:CDKN3-798RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CDKN3 Protein, His-tagged
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Cat.#:CDKN3-4556CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CDKN3
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Cat.#:CDKN3-7370ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CDKN3
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Cat.#:CDKN3-7609HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CDKN3 293 Cell Lysate
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Protein Function

CDKN3 has several biochemical functions, for example, protein binding, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDKN3 itself. We selected most functions CDKN3 had, and list some proteins which have the same functions with CDKN3. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein KCTD14; USP28; TOMM7; ZFYVE28; RICTOR; TMED1; GRIK3; SH3PXD2B; ZNF496; NDUFS2
Function protein serine/threonine phosphatase activity
Related Protein TIMM50; CDKN3; PPM1F; TAB1; DUSP23; LCK; PPM1BB; PPEF1; PPM1AB; DUSP23A
Function protein tyrosine phosphatase activity
Related Protein PALD1B; DUSP18; PTPRJA; CDKN3; DUSP2; PTPN2; CDC25A; PTPRZ1; PTPN2B; DUSP3B
Function protein tyrosine/serine/threonine phosphatase activity
Related Protein EPM2A; DUSP10; CDC14AB; DUSP13A; DUSP4; CDC14AA; CDC14C; DUSP14; CDC14A; SACM1LB

Interacting Protein

CDKN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDKN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDKN3.
CDK2; CDC28; CDK1; CDK3