cldn22
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  • Official Full Name
  • claudin 22
  • Background
  • This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3 UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.
  • Synonyms
  • CLDN22; claudin 22; claudin-22; CLDN21; CLD22_HUMAN; FLJ51450
Cat.#:CLDN22-3244HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CLDN22 Protein, MYC/DDK-tagged
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Cat.#:CLDN22-3533MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CLDN22 Protein
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Cat.#:CLDN22-894RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CLDN22 Protein, His-tagged
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Involved Pathway

CLDN22 involved in several pathways and played different roles in them. We selected most pathways CLDN22 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell adhesion molecules (CAMs)
GLYCAM1; CD274; ICOSLG; NLGN1; BF1; CLDN1; NRXN2; CLDNF; LRRC4C; MHC2A
Tight junction
CLDN5B; LLGL2; ZAK; CLDN11A; CLDN7; CLDN19; PPP2R2CA; MAGI2; ACTB; RAB3B
Leukocyte transendothelial migration
CLDN4; AASS; MYL10; GNAI1; CLDN14; CLDN2; CXCR4; RAP1A; PIK3CA; NIPAL1
Hepatitis C
PPP2CB; IFNA7; IFNA1; TRADD; SOS1; IFIT1; TP53; IFNA21; MAPK11; MAPK1

Protein Function

CLDN22 has several biochemical functions, for example, molecular_function, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN22 itself. We selected most functions CLDN22 had, and list some proteins which have the same functions with CLDN22. You can find most of the proteins on our site.
Function
Related Protein
Function molecular_function
Related Protein SCGB2A2; LSM12B; TMEM14CA; SAGA; TMTC3; SCRN1; TIFAB; SLAIN1; SCML4; CCDC85CB
Function structural molecule activity
Related Protein KRT39; SNTB1; CDC42SE1; FGB; KRT80; NEFLB; KRT38; SPRR2H; KRT82; PRR9

CLDN22 Related Articles

Tominaga, A; Konishi, Y; et al. Autonomous cure of damaged human intestinal epithelial cells by TLR2 and TLR4-dependent production of IL-22 in response to Spirulina polysaccharides. INTERNATIONAL IMMUNOPHARMACOLOGY 17:1009-1019(2013).
Bauerschlag, D; Brautigam, K; et al. Systematic analysis and validation of differential gene expression in ovarian serous adenocarcinomas and normal ovary. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 139:347-355(2013).