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Official Full Name carboxymethylenebutenolidase homolog (Pseudomonas)
Background CMBL (EC is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010
Synonyms CMBL; carboxymethylenebutenolidase homolog (Pseudomonas); carboxymethylenebutenolidase like (Pseudomonas); carboxymethylenebutenolidase homolog; FLJ23617; CMBL_HUMAN; carboxymethylenebutenolidase-like (Pseudomonas)
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Cmbl-2205M Recombinant Mouse Cmbl Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human CMBL-4919H Recombinant Human CMBL Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CMBL-1534H Recombinant Human CMBL Protein, GST-tagged Wheat Germ GST
    Human CMBL-2504H Recombinant Human CMBL, His tagged E.coli His
    Human CMBL-6960H Recombinant Human Carboxymethylenebutenolidase Homolog (Pseudomonas), His-tagged E.coli His
    Human CMBL-7421HCL Recombinant Human CMBL 293 Cell Lysate HEK293 N/A
    Mouse CMBL-3622M Recombinant Mouse CMBL Protein Mammalian Cell His
    Rat CMBL-1478R Recombinant Rat CMBL Protein Mammalian Cell His
    Rhesus Macaque CMBL-927R Recombinant Rhesus monkey CMBL Protein, His-tagged Mammalian Cell His
    Zebrafish CMBL-6072Z Recombinant Zebrafish CMBL Mammalian Cell His

    CMBL involved in several pathways and played different roles in them. We selected most pathways CMBL participated on our site, such as Biosynthesis of antibiotics, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with CMBL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Biosynthesis of antibiotics DAO1; pykF; UAP1L1; ECHS1; NME6; DLD; SDSL; DLST; EHHADH; ACAA2
    Metabolic pathways ATP5G3A; FECH; HMGCL; IMPDH2; GALNTL4; NT5C1B-RDH14; DEGS1; AMPD1; COX6B1; AANAT

    CMBL has several biochemical functions, for example, hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CMBL itself. We selected most functions CMBL had, and list some proteins which have the same functions with CMBL. You can find most of the proteins on our site.

    Function Related Protein
    hydrolase activity GCH2; UNGA; GM5077; EAR3; CPSF5; EIF4A1B; PPAPDC2; MRPL46; HELZ; PSMB11

    CMBL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CMBL here. Most of them are supplied by our site. Hope this information will be useful for your research of CMBL.

    CD2BP2; ATIC; ARRB1; CUL2; EIF4A2; TRIP6; SMYD2; PUF60; 2_aha_camp; 8-aha-camp; 8-aha-omethyladenosine; SAP30; Chmp6; H2AFX; SNCA; SMS; Crocc; KIF20B

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