|Official Full Name||coenzyme Q2 homolog, prenyltransferase (yeast)|
|Background||This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement.|
|Synonyms||COQ2; coenzyme Q2 homolog, prenyltransferase (yeast); 4-hydroxybenzoate polyprenyltransferase, mitochondrial; 4 hydroxybenzoate polyprenyltransferase; CL640; FLJ26072; MGC91278; 2310002F18Rik; FLJ13014; hCOQ2; MGC124824; OTTMUSP00000032111; Para-hydroxybenzoate--polyprenyltransferase, mitochondrial; PHB:polyprenyltransferase; RGD1306722; COQ2 homolog; para-hydroxybenzoate-polyprenyltransferase, mitochondrial|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
COQ2 involved in several pathways and played different roles in them. We selected most pathways COQ2 participated on our site, such as Ubiquinone and other terpenoid-quinone biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with COQ2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Ubiquinone and other terpenoid-quinone biosynthesis||COQ2; HPDB; GGCX; HPD; TAT; COQ5; HPDA; VKORC1L1; COQ6; COQ7|
|Metabolic pathways||GLCEB; P4HA1B; NAGK; ALG9; AKR1B7; CYP2C55; AMY2A5; NMNAT2; C1GALT1; PLCD3|
COQ2 has several biochemical functions, for example, 4-hydroxybenzoate decaprenyltransferase activity, 4-hydroxybenzoate nonaprenyltransferase activity, prenyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by COQ2 itself. We selected most functions COQ2 had, and list some proteins which have the same functions with COQ2. You can find most of the proteins on our site.
|4-hydroxybenzoate decaprenyltransferase activity||COQ2|
|4-hydroxybenzoate nonaprenyltransferase activity||COQ2|
|prenyltransferase activity||COQ2; UBIAD1; PTAR1; PGGT1B|
|transferase activity||ST3GAL5L; GLT25D2; KITA; GSTP2; UGT2B3; NTRK2B; GXYLT2; DNAJC3B; DCLK2; ELOVL4|
COQ2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COQ2 here. Most of them are supplied by our site. Hope this information will be useful for your research of COQ2.