Recombinant Full Length Human COQ2 Protein, GST-tagged

• Cat.No.: COQ2-1973HF
• Product Overview: Human COQ2 full-length ORF ( AAH08804.1, 1 a.a. - 371 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq, Oct 2009]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 66.9 kDa
• Protein Length: 371 amino acids
• AA Sequence: MLGSRAAGFARGLRALALAWLPGWR GRSFALARAAGAPHGGDLQPPACPE PRGRQLSLSAAAVVDSAPRPLQPYL RLMRLDKPIGTWLLYLPCTWSIGLA AEPGCFPDWYMLSLFGTGAILMRGA GCTINDMWDQDYDKKVTRTANRPIA AGDISTFQSFVFLGGQLTLALGVLL CLNYYSIALGAGSLLLVITYPLMKR ISYWPQLALGLTFNWGALLGWSAIK GSCDPSVCLPLYFSGVMWTLIYDTI YAHQDKRDDVLIGLKSTALRFGENT KPWLSGFSVAMLGALSLVGVNSGQT APYYAALGAVGAHLTHQIYTLDIHR PEDCWNKFISNRTLGLIVFLGIVLG NLWKEKKTDKTKKGIENKIEN
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COQ2 coenzyme Q2 homolog, prenyltransferase (yeast) [ Homo sapiens ]
• Official Symbol: COQ2
• Synonyms: COQ2; coenzyme Q2 homolog, prenyltransferase (yeast); 4-hydroxybenzoate polyprenyltransferase, mitochondrial; 4 hydroxybenzoate polyprenyltransferase; CL640; FLJ26072; hCOQ2; COQ2 homolog; PHB:polyprenyltransferase; para-hydroxybenzoate-polyprenyltransferase, mitochondrial; para-hydroxybenzoate--polyprenyltransferase, mitochondrial; FLJ13014
• Gene ID: 27235
• mRNA Refseq: NM_015697
• Protein Refseq: NP_056512
• MIM: 609825
• UniProt ID: Q96H96