CRABP2
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Official Full Name
cellular retinoic acid binding protein 2
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Overview
This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene. -
Synonyms
CRABP2; cellular retinoic acid binding protein 2; cellular retinoic acid-binding protein 2; CRABP II; Cellular retinoic acid binding protein II; Cellular retinoic acid-binding protein II; CRABP-II; CRABPII; RABP2_HUMAN; RBP6; OTTHUMP00000038730; OTTHUMP00000038732;
- Recombinant Proteins
- Cell & Tissue Lysates
- Antibody
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mouse
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- CRABP2 Related Articles
CRABP2 involved in several pathways and played different roles in them. We selected most pathways CRABP2 participated on our site, such as Signal Transduction, Signaling by Retinoic Acid, Vitamin A and carotenoid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRABP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Signal Transduction | ARHGAP8;CRABP2;GPR132B;ARHGAP29B;RLN2;MKL1B;RPE65B;FFAR3;SHARPIN |
Signaling by Retinoic Acid | RDH7;CRABP1A;ALDH8A1;DHRS9;CRABP2A;CRABP1;RDH10;RARG;FABP11B |
Vitamin A and carotenoid metabolism | CRABP2;RDH12;CRABP1;RBP7;RARG;RDH10;DHRS3;BCO2 |
CRABP2 has several biochemical functions, for example, protein binding, retinal binding, retinoic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRABP2 itself. We selected most functions CRABP2 had, and list some proteins which have the same functions with CRABP2. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | KRT15;RAB9A;OAZ2;SPTSSB;WWP1;HSP90AA1.1;USP9X;FECH;DCTPP1 |
retinal binding | RBP3;CRABP2;RBP2B;RBP1;RBP4;RBP2A;CRABP1;RBP5;RBP2 |
retinoic acid binding | UGT1A2;RARA;NR2F2;CRABP1A;UGT1A9;LRAT;UGT1A3;CYP26B1;CYP26A1 |
retinoid binding | RBP3;LCN5;CRABP2;RBP2;RBP5;RBP1;RBP4L;CRABP1;PTGDS |
retinol binding | RBP1;RBP7;CRABP2;CRABP1;ADH7;RBP2;ADH4;RBP4;RBP5 |
transporter activity | AQP1A.2;ABCA3;AP2S1;XK;FABP7A;ABCC6;TMEM184A;SLC5A12;ABCA6 |
CRABP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRABP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRABP2.
CCDC155; CCDC132
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