crabp2
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  • Official Full Name
  • cellular retinoic acid binding protein 2
  • Background
  • This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
  • Synonyms
  • CRABP2; cellular retinoic acid binding protein 2; cellular retinoic acid-binding protein 2; CRABP II; Cellular retinoic acid binding protein II; Cellular retinoic acid-binding protein II; CRABP-II; CRABPII; RABP2_HUMAN; RBP6; OTTHUMP00000038730; OTTHUMP00000038732
Cat.#:CRABP2-1830HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CRABP2 Protein, GST-tagged
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Cat.#:CRABP2-3333HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CRABP2 Protein, MYC/DDK-tagged
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Cat.#:CRABP2-368HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Cellular Retinoic Acid Binding Protein 2
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Cat.#:CRABP2-11551HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRABP2, GST-tagged
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Cat.#:CRABP2-26985THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRABP2
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Cat.#:CRABP2-3086HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CRABP2, His tagged
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Cat.#:CRABP2-3876MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CRABP2 Protein
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Cat.#:Crabp2-4039MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Crabp2, His tagged
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Cat.#:CRABP2-1584RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CRABP2 Protein
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Cat.#:CRABP2-1014RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CRABP2 Protein, His-tagged
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Cat.#:CRABP2-7295HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CRABP2 293 Cell Lysate
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Involved Pathway

CRABP2 involved in several pathways and played different roles in them. We selected most pathways CRABP2 participated on our site, such as Signal Transduction, Signaling by Retinoic Acid, Vitamin A and carotenoid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRABP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Signal Transduction
METAP2A; LRIG1; FOXH1; OPN4B; HEYL; MYO9B; EVC2; CCL19A.2; PDK2; TAS2R7
Signaling by Retinoic Acid
DHRS3A; DHRS9; CRABP2B; PDK4; FABP11A; DHRS4; PDK2; RDH10; PDK2B; RDH14A
Vitamin A and carotenoid metabolism
RARG; RDH10; RDH12; CRABP1; RBP7; CRABP2; BCO2; DHRS3

Protein Function

CRABP2 has several biochemical functions, for example, protein binding, retinal binding, retinoic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRABP2 itself. We selected most functions CRABP2 had, and list some proteins which have the same functions with CRABP2. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein CCDC86; MCM5; SCRIB; HERC5; CTH; NUDT2; CACNB2; RMND5A; GATSL3; PHF20L1
Function retinal binding
Related Protein RBP4; RBP2B; RBP1; CRABP1; RBP3; RBP2A; RBP7; RBP2; RBP5; CRABP2
Function retinoic acid binding
Related Protein UGT1A1; CYP26B1; RARA; CRABP1B; LRAT; NR2F2; PTGDSB; SERPINA5; LCN12; CRABP2
Function retinoid binding
Related Protein PTGDS; RBP1; CRABP2; LCN5; RBP4L; CRABP1; RBP3; RBP5; RBP2
Function retinol binding
Related Protein RBP3; RBP4; C8G; RBP7; LRAT; CRABP1; RLBP1; CRABP2; RBP5; ADH7
Function transporter activity
Related Protein ABCA7; MFSD10; SLCO1B2; SEC14L4; ABCB1; OSTA; AQP12B; AP1S2; SLCO1F1; ABCD1

Interacting Protein

CRABP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRABP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRABP2.
CCDC155; CCDC132

CRABP2 Related Articles

Yu, MY; Ishibashi-Ueda, H; et al. Transient expression of cellular retinol-binding protein-1 during cardiac repair after myocardial infarction. PATHOLOGY INTERNATIONAL 62:246-253(2012).
Gromov, P; Gromova, I; et al. Up-regulated Proteins in the Fluid Bathing the Tumour Cell Microenvironment as Potential Serological Markers for Early Detection of Cancer of the Breast. MOLECULAR ONCOLOGY 4:65-89(2010).