CYSLTR1
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Official Full Name
cysteinyl leukotriene receptor 1
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Overview
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. -
Synonyms
CYSLTR1; cysteinyl leukotriene receptor 1; CysLT(1); CysLT1; CYSLT1R; CYSLT 1; CYSLTR 1; CYSLTR; CysLTR vide supra; Cysteinyl leukotriene D4 receptor; HG55; HMTMF81; LTD4 receptor; MGC46139; G-protein coupled receptor HG55;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Cavia porcellus (Guinea pig)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Sus scrofa (Pig)
- Zebrafish
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- In vitro E. coli expression system
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CYSLTR1-2299H | Recombinant Human CYSLTR1 Protein | Wheat Germ | N/A |
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| Human | CYSLTR1-2300H | Recombinant Human CYSLTR1 Protein, GST-tagged | Wheat Germ | GST |
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| Human | CYSLTR1-2489HF | Recombinant Full Length Human CYSLTR1 Protein, GST-tagged | In Vitro Cell Free System | GST | 337 amino acids |
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| Human | CYSLTR1-2488HF | Recombinant Full Length Human CYSLTR1 Protein | In Vitro Cell Free System | 337 amino acids |
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| Human | CYSLTR1-1535H | Recombinant Human CYSLTR1 Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | His | 1-337aa |
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| Mouse | CYSLTR1-4248M | Recombinant Mouse CYSLTR1 Protein | Mammalian Cell | His |
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| Mouse | CYSLTR1-2167M-B | Recombinant Mouse CYSLTR1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | CYSLTR1-2167M | Recombinant Mouse CYSLTR1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | CYSLTR1-1760R | Recombinant Rat CYSLTR1 Protein | Mammalian Cell | His |
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| Rat | CYSLTR1-1419R | Recombinant Rat CYSLTR1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | CYSLTR1-1419R-B | Recombinant Rat CYSLTR1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Cavia porcellus (Guinea pig) | RFL19736CF | Recombinant Full Length Guinea Pig Cysteinyl Leukotriene Receptor 1(Cysltr1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-340) |
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| Homo sapiens (Human) | RFL32416HF | Recombinant Human Cysteinyl Leukotriene Receptor 1(Cysltr1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-337aa) |
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| Mus musculus (Mouse) | RFL21277MF | Recombinant Full Length Mouse Cysteinyl Leukotriene Receptor 1(Cysltr1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-352) |
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| Rattus norvegicus (Rat) | RFL14915RF | Recombinant Full Length Rat Cysteinyl Leukotriene Receptor 1(Cysltr1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-339) |
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| Sus scrofa (Pig) | RFL3184SF | Recombinant Full Length Pig Cysteinyl Leukotriene Receptor 1(Cysltr1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-340) |
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| Zebrafish | CYSLTR1-2820Z | Recombinant Zebrafish CYSLTR1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CYSLTR1 Related Articles
CYSLTR1 involved in several pathways and played different roles in them. We selected most pathways CYSLTR1 participated on our site, such as Calcium signaling pathway, Class A/1 (Rhodopsin-like receptors), Eicosanoid ligand-binding receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYSLTR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | PHKA2;AVPR1A;CALM4;SLC8A1A;ADORA2A;ITPR1;TRHR2;HRH1;HTR2C |
| Class A/1 (Rhodopsin-like receptors) | GPR31;CXCL13;INSL3;CNR2;OPN1SW;MLN;NMS;ADORA2B;GPR68 |
| Eicosanoid ligand-binding receptors | GPR17;CYSLTR1;PTGDR2;OXER1;LTB4R |
| Endothelins | COL3A1;EDN2;EDNRA;EDN1;CYSLTR1;COL1A2;EDNRB;EDN3 |
| G alpha (q) signalling events | AGTR1;GPR65;GPRC6A;PMCH;ABHD6B;PROK1;EDNRA;KALRNB;NMUR1 |
| GPCR downstream signaling | GCGA;ARHGEF17;TAC3;RGS20;RGS14;GCGB;OPN1MW;SSTR2;OPN1MW2 |
| GPCR ligand binding | S1PR3;EDN3;CXCL11.8;GNB5B;ADM2A;NMBA;CCL35.2;CCK;PENKB |
| GPCRs, Class A Rhodopsin-like | GPR63;CHRM4;SSTR4;NPFFR2;CNR1;OR3A4P;CX3CR1;CNR2;GPR12 |
CYSLTR1 has several biochemical functions, for example, G-protein coupled peptide receptor activity, cysteinyl leukotriene receptor activity, leukotriene receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CYSLTR1 itself. We selected most functions CYSLTR1 had, and list some proteins which have the same functions with CYSLTR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled peptide receptor activity | CYSLTR1;FSHR;NPR3;RXFP4;LTB4R2;LHCGR;GPR84;CYSLTR2;NPR1 |
| cysteinyl leukotriene receptor activity | MCHR2;CYSLTR2;CYSLTR1 |
| leukotriene receptor activity | LTB4R2;CYSLTR2;CYSLTR1;LTB4R |
| protein binding | ATXN2;TAL2;FBXW8;CARD11;FHIT;LOC780933;TAB1;E2F7;ZNF750 |
CYSLTR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYSLTR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYSLTR1.
CYSLTR2
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