disc1
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  • Official Full Name
  • disrupted in schizophrenia 1
  • Background
  • interacts with a variety of cytoskeletal proteins; truncated mutant form is associated with Schizophrenia
  • Synonyms
  • DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 protein; SCZD9; C1orf136; FLJ13381; FLJ21640; FLJ25311; FLJ41105; KIAA0457
Cat.#:DISC1-470HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DISC1 Protein, His-tagged
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Cat.#:Disc1-471MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Disc1 Protein, His-tagged
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Cat.#:Disc1-472RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Disc1 Protein, His-tagged
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Cat.#:DISC1-1873RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DISC1 Protein
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Cat.#:DISC1-1271RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DISC1 Protein, His-tagged
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Cat.#:DISC1-7233ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DISC1
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Cat.#:DISC1-6918HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human DISC1 293 Cell Lysate
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Protein Function

DISC1 has several biochemical functions, for example, kinesin binding, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DISC1 itself. We selected most functions DISC1 had, and list some proteins which have the same functions with DISC1. You can find most of the proteins on our site.
Function
Related Protein
Function kinesin binding
Related Protein TOR1A; ARPC2; AP1G1; JIP1; ATCAY; CLSTN1; SERPINB1A; GOLSYN; DISC1; SNCA
Function protein binding
Related Protein TA; LUC7L2; C16orf72; IRF7; SYNM; SLA2; HRK; NAA30; LRRC4; RB1CC1
Function protein complex binding
Related Protein AP2B1; CPS1; ABI2; BRK1; TUB; STRN; C8A; KRIT1; KAT6B; LRP2
Function protein complex scaffold
Related Protein WWC2; MAGI3; SLC9A3R1; C9orf142; WWC3; DISC1; HOMER1; ISCU; AKAP6; TELO2

Interacting Protein

DISC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DISC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DISC1.
PCNT; TRAF3IP1; NDEL1

DISC1 Related Articles

Bradshaw, NJ; Bader, V; et al. Aggregation of the Protein TRIOBP-1 and Its Potential Relevance to Schizophrenia. PLOS ONE 9:-(2014).
El-Hassar, L; Simen, AA; et al. Disrupted in Schizophrenia 1 Modulates Medial Prefrontal Cortex Pyramidal Neuron Activity Through cAMP Regulation of Transient Receptor Potential C and Small-Conductance K+ Channels. BIOLOGICAL PSYCHIATRY 76:476-485(2014).