DLG4 Protein, Dlg4 discs, large homolog 4 (Drosophila)

DLG4

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DLG4

Official Full Name Dlg4 discs, large homolog 4 (Drosophila)
Synonyms DLG4; discs, large homolog 4 (Drosophila); disks large homolog 4; SAP-90; PSD-95 beta; PSD-95 alpha 2b; discs large homolog 4; synapse-associated protein 90; postsynaptic density protein 95; Dlgh4; PSD95; SAP90; PSD-95; SAP90A;
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DLG4-152H Recombinant Human DLG4 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human DLG4-159H Recombinant Human DLG4 protein, GST-tagged Wheat Germ GST
    Human DLG4-18H Recombinant Human DLG4 protein, His-tagged E.coli His
    Human DLG4-31002TH Recombinant Human DLG4 Wheat Germ N/A
    Human DLG4-6910HCL Recombinant Human DLG4 293 Cell Lysate HEK293 N/A
    Mouse DLG4-4622M Recombinant Mouse DLG4 Protein Mammalian Cell His
    Rat DLG4-1881R Recombinant Rat DLG4 Protein Mammalian Cell His

    DLG4 involved in several pathways and played different roles in them. We selected most pathways DLG4 participated on our site, such as ARMS-mediated activation, Activation of Ca-permeable Kainate Receptor, Activation of Kainate Receptors upon glutamate binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLG4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ARMS-mediated activation FRS3; PSMD9; FGF20A; PSME3; PEA15A; NRG2A; DUSP5; FGF10B; FRS2A; DUSP4
    Activation of Ca-permeable Kainate Receptor DLG3; NCALDA; DLG1L; DLG4
    Activation of Kainate Receptors upon glutamate binding NCALDA; GNB5; DLG4; DLG1L; DLG3
    Activation of NMDA receptor upon glutamate binding and postsynaptic events NEFLB; AKAP9; DLG4; SLC14A2; CREB1B; CAMKK1B; PDPK1A; CREB1; NETO2; ADCY3
    Axon guidance ARPC1A; KALRN; PAQR3B; TRPC5; SCN8A; NFATC2; SPTB; EPHA5; SCN9A; EPHB4B
    CREB phosphorylation through the activation of CaMKII NEFLB; CREB1B; SLC14A2; AKAP9; NETO2; DLG4
    CREB phosphorylation through the activation of Ras PDPK1A; DLG4; AKAP9; SLC14A2; NEFLB
    Cocaine addiction SLC6A3; GRIN2B; DRD1A; CDK5; GRM3; PDYN; TH; GNAS; GPSM1; RGS9

    DLG4 has several biochemical functions, for example, D1 dopamine receptor binding, P2Y1 nucleotide receptor binding, PDZ domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLG4 itself. We selected most functions DLG4 had, and list some proteins which have the same functions with DLG4. You can find most of the proteins on our site.

    Function Related Protein
    D1 dopamine receptor binding ATP1A3; ARRB2; DLG4; CAV2; PTPN11; DRD3; GNAS; AGTR1A
    P2Y1 nucleotide receptor binding DLG4
    PDZ domain binding PLEKHA1; ATP2B2; SSTR2; USHBP1; LPAR1; KIDINS220B; CFTR; LLGL2; FZD2; CLCN3
    acetylcholine receptor binding RIC3; NRXN1; RER1; APP; DLG4; KCNS1; UBXN2A; RAPSN; JAK2
    beta-1 adrenergic receptor binding DLG4; MAGI2
    guanylate kinase activity DLG4; GUK1B; MPP2; DLG1L; GUK1A; MPP1; MPP3; DLG4B; DLG1; DLG3
    ionotropic glutamate receptor binding DLG4; SHANK2; DLG1; FLOT2; DLG2; FUS; GNAS; CANX; DLG3; DRD2
    kinase binding TENC1; CHP1; TAX1BP1; STUB1; PTPN22; TRIP6; CEBPB; WWC2; PRKAA1; PPP1R9B
    neuroligin family protein binding NRXN1; DLG4; NRXN3; NRXN2
    protein C-terminus binding XRCC5; HSPG2; PICK1; MIF4GD; KSR1; PEX26; SDCBP; DYNLL1; BCL10; MSH2
    protein binding DIAP1; EDARADD; ACCS; DAZAP2; DCBLD2; CANX; NACC2; SPTAN1; RNF170; TEKT1
    protein complex binding CPS1; PPFIA2; HADHA; SLC9A3R1; NCOA1; UGT1A6B; PGAM5; CDK5RAP1; PPIB; SKAP1
    protein phosphatase binding TP53; PPP1R3C; MAP3K5; ANAPC5; VCAN; STAT3; ITPR1; PPARG; CDH2; PARD3
    scaffold protein binding DLG4; GRIN2A; IKBKB; KRT18; NLGN4Y; KRT5; CHRNA7; SCN5A; NOS3; ADCY6

    DLG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLG4.

    Kcna4; ERBB4; Dlgap1; KCNA4

    Dorostkar, MM; Burgold, S; et al. Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer's disease mouse model. BRAIN 137:3319-3326(2014).

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