| Description : |
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
85.2 kDa |
| AA Sequence : |
MSQRPRAPRSALWLLAPPLLRWAPP LLTVLHSDLFQALLDILDYYEASLS ESQKYRYQDEDTPPLEHSPAHLPNQ ANSPPVIVNTDTLEAPGYELQVNGT EGEMEYEEITLERGNSGLGFSIAGG TDNPHIGDDPSIFITKIIPGGAAAQ DGRLRVNDSILFVNEVDVREVTHSA AVEALKEAGSIVRLYVMRRKPPAEK VMEIKLIKGPKGLGFSIAGGVGNQH IPGDNSIYVTKIIEGGAAHKDGRLQ IGDKILAVNSVGLEDVMHEDAVAAL KNTYDVVYLKVAKPSNAYLSDSYAP PDITTSYSQHLDNEISHSSYLGTDY PTAMTPTSPRRYSPVAKDLLGEEDI PREPRRIVIHRGSTGLGFNIVGGED GEGIFISFILAGGPADLSGELRKGD QILSVNGVDLRNASHEQAAIALKNA GQTVTIIAQYKPEEYSRFEAKIHDL REQLMNSSLGSGTASLRSNPKRGFY IRALFDYDKTKDCGFLSQALSFRFG DVLHVIDASDEEWWQARRVHSDSET DDIGFIPSKRRVERREWSRLKAKDW GSSSGSQGREDSVLSYETVTQMEVH YARPIIILGPTKDRANDDLLSEFPD KFGSCVPHTTRPKREYEIDGRDYHF VSSREKMEKDIQAHKFIEAGQYNSH LYGTSVQSVREVAEQGKHCILDVSA NAVRRLQAAHLHPIAIFIRPRSLEN VLEINKRITEEQARKAFDRATKLEQ EFTECFSAIVEGDSFEEIYHKVKRV IEDLSGPYIWVPARERLTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
