| Description : |
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
111.8 kDa |
| Protein Length : |
767 amino acids |
| AA Sequence : |
MSQRPRAPRS ALWLLAPPLL RWAPPLLTVL HSDLFQALLD ILDYYEASLS ESQKYRYQDE DTPPLEHSPA HLPNQANSPP VIVNTDTLEA PGYELQVNGT EGEMEYEEIT LERGNSGLGF SIAGGTDNPH IGDDPSIFIT KIIPGGAAAQ DGRLRVNDSI LFVNEVDVRE VTHSAAVEAL KEAGSIVRLY VMRRKPPAEK VMEIKLIKGP KGLGFSIAGG VGNQHIPGDN SIYVTKIIEG GAAHKDGRLQ IGDKILAVNS VGLEDVMHED AVAALKNTYD VVYLKVAKPS NAYLSDSYAP PDITTSYSQH LDNEISHSSY LGTDYPTAMT PTSPRRYSPV AKDLLGEEDI PREPRRIVIH RGSTGLGFNI VGGEDGEGIF ISFILAGGPA DLSGELRKGD QILSVNGVDL RNASHEQAAI ALKNAGQTVT IIAQYKPEEY SRFEAKIHDL REQLMNSSLG SGTASLRSNP KRGFYIRALF DYDKTKDCGF LSQALSFRFG DVLHVIDASD EEWWQARRVH SDSETDDIGF IPSKRRVERR EWSRLKAKDW GSSSGSQGRE DSVLSYETVT QMEVHYARPI IILGPTKDRA NDDLLSEFPD KFGSCVPHTT RPKREYEIDG RDYHFVSSRE KMEKDIQAHK FIEAGQYNSH LYGTSVQSVR EVAEQGKHCI LDVSANAVRR LQAAHLHPIA IFIRPRSLEN VLEINKRITE EQARKAFDRA TKLEQEFTEC FSAIVEGDSF EEIYHKVKRV IEDLSGPYIW VPARERL |
| Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
